ATP driven clathrin dependent entry of carbon nanospheres prefer cells with glucose receptors.

Background: Intrinsically fluorescent glucose derived carbon nanospheres (CSP) efficiently enter mammalian cells and also cross the blood brain barrier (BBB). However, the mechanistic details of CSP entry inside mammalian cells and its specificity are not known.

Results: In this report, the biochemical and cellular mechanism of CSP entry into the living cell have been investigated.