Background: Myocardial perfusion imaging (MPI) is one of the most commonly performed investigations in nuclear medicine procedures. Due to the longer half-life of the emerging positron emitter copper-64 and its availability from low energy cyclotron, together with its well-known coordination chemistry, we have synthesized Cu-labeled NOTA- and Cu-NOTAM-rhodamine conjugates as potential cardiac imaging agents using PET.
Results: Cu-NOTA- and Cu-NOTAM-rhodamine conjugates were synthesized using a traightforward and one-step simple reaction.
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