The Efficacy and Safety of Inclisiran for Low-Density Lipoprotein (LDL) in Patients With Atherosclerotic Cardiovascular Disease (ASCVD): A Systematic Review of Randomized Controlled Trials.

This systematic review synthesizes current evidence to evaluate the safety and efficacy of inclisiran for lowering low-density lipoprotein cholesterol (LDL-C). A thorough search was conducted across four main databases - PubMed, Web of Science, SCOPUS, and Science Direct - for relevant studies published in the literature within the last five years (2020-2024). We included seven studies with a total of 6831 participants, of which 4661 (68.