Publications by authors named "Banda M"

Coal fly ash (CFA) is a predominant waste by-product of coal combustion which is disposed of in open ash dams that utilize large pieces of land. This waste material is classified as a hazardous substance in South Africa as well as in other countries due to its fine particles that are easily blown to the atmosphere and the unacceptable levels of heavy metals and persistent organic pollutants. Contaminants in CFA can pollute surface and ground water, agricultural sites, soil and therefore pose risks to the health of humans and the environment.

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The disposal of coal fly ash (CFA) generated from coal-fired power stations has serious impact on the ecosystem, by converting large pieces of land to barren ash dams with the potential to contaminate groundwater, surface water, air and soil. The aim of this study was to clarify the potential of phytoremediation using (Thunb.) Less.

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  • The control of African trypanosomiasis (AT) in Eastern and Southern Africa, particularly Zambia, is complicated due to the presence of wild and domestic animal reservoirs, especially free-roaming dogs that can contract and transmit the disease.
  • A study involving 162 dogs in Zambia's Mambwe district found a high prevalence of trypanosome infections, with 74.7% testing positive for antibodies and 70.9% showing DNA evidence of infection from various trypanosome species, including human-infective strains.
  • The findings highlight the significant role of domesticated dogs as reservoirs for AT, indicating that control efforts should expand beyond livestock to include these dogs to more effectively combat the disease in endemic areas.
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  • The study aimed to estimate the prevalence of gestational diabetes mellitus (GDM) and compare pregnancy outcomes based on different treatment methods in a teaching hospital in Telangana.
  • It involved a prospective analysis of GDM cases diagnosed using specific criteria, categorizing women into four groups based on treatment: diet, metformin, metformin plus insulin, and insulin alone.
  • Results indicated that metformin and dietary management achieved better glycaemic control and had fewer complications compared to insulin treatment, suggesting metformin as a viable, cost-effective alternative for managing GDM.
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In the last few decades, the field of ancient DNA has taken a new direction towards using sedimentary ancient DNA (sedaDNA) for studying human and mammalian population dynamics as well as past ecosystems. However, the screening of numerous sediment samples from archaeological sites remains a time-consuming and costly endeavor, particularly when targeting hominin DNA. Here, we present a novel high-throughput method that facilitates the fast and efficient analysis of sediment samples by applying a pooled testing approach.

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  • Micronutrient deficiencies, especially in zinc and iron, are common in sub-Saharan Africa due to low dietary intake, with wheat often lacking these nutrients.
  • The study involved developing Malawian wheat introgression lines that were tested for higher concentrations of zinc and iron in low-nutrient soils, revealing that 98% of these lines had better zinc levels compared to established varieties.
  • Among these lines, 23% achieved both high yields and increased grain zinc, with some also showing improvements in iron, indicating the potential for enhanced nutritional quality in wheat for regions affected by MNDs.
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Environmental pollution has become a global issue due to continuing anthropogenic activities that result in the production of enormous amounts of waste and the subsequent release of hazardous trace metals. The increasing levels of trace metals in the environment must be monitored regularly and reduced to prevent contamination of food chain. Numerous conventional technologies that are widely used for the removal of trace metals from environmental matrices have many drawbacks.

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. Preterm infants are at risk of hypothermia. This study described the available infant warming devices (IWDs) and explored the barriers and facilitators to their implementation in neonates in Malawi.

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Aflatoxins B1 (AFB1) are fungi-produced toxins found in crops like peanuts, maize, and tree nuts. They constitute a public health concern due to their genotoxic and carcinogenic effects. A deterministic exposure risk assessment to AFB1 through the consumption of peanuts was conducted on children using the Margin of Exposure (MOE) and the liver cancer risk approaches.

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Air pollution remains a major public health risk. People living in urban spaces are among those most affected by exposure to unhealthy levels of air pollution. However, many urban spaces especially in low- and middle-income countries lack high resolution and long-term data on the state of air quality.

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Good dog-keeping practices and access to veterinary care are essential for the well-being of dogs. As the main causes of morbidity and mortality in the rural canine population in Zambia are poorly understood, we followed a cohort of 162 indigenous dogs for six months in wildlife-populated and tsetse-infested villages of Mambwe district, eastern Zambia to gain deeper insights. Dogs lacked basic home and veterinary care, they were often starved and burdened with ticks, and some passed live adult worms in their stool.

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Improving breastfeeding practices is key to reducing child mortality globally. Sub-optimal exclusive breastfeeding rates may be associated with inadequate hospital-based postpartum breastfeeding support, particularly in resource-limited health settings such as Malawi. While almost all children in Malawi are breastfed, it is a concern that exclusive breastfeeding rates in Malawi are declining.

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The effect of the converging orifice geometry in a model silo on the discharge rate of monosized spherical particles was studied experimentally and numerically. The cylindrical container was equipped with interchangeable inserts with converging discharge orifices of various upper diameters in the upper base and a constant lower diameter in the lower base. Plastic PLA beads and agricultural granular materials: wheat, rapeseeds, and linseeds were tested.

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Background: Substandard and falsified (SF) medical products are removed from circulation through a process called 'product recall' by medicines regulatory agencies. In Zambia, the Zambia Medicines Regulatory Authority (ZAMRA) is responsible for recalling SF medical products from the Zambian market through passive and active surveillance methods. This study aimed to describe the prevalence of recalls of SF medical products and to analyse the frequently recalled therapeutic categories, dosage forms, categories of defects that led to the recalls and their sources with respect to the country of the marketing authorisation holder (MAH) or manufacturer.

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Ethylene glycol (EG) toxicity is an important cause of toxic alcohol poisoning in the USA with over 5,000 exposures reported annually. While classically characterized by solitary accidental or intentional ingestions, mass toxic alcohol poisoning outbreaks and more rarely collective consumptions (typically of methanol) have been described. We describe an ethylene glycol poisoning from collective ingestion that involved soldiers presenting at William Beaumont Army Medical Center in El Paso, Texas.

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  • The study assessed the knowledge and practices regarding COVID-19 among 478 healthcare students at the University of Zambia, following the pandemic's disruption of physical classes globally.
  • Results showed that the mean knowledge score was 87.9, with medical students scoring the highest, while the mean practice score was 60.0, significantly higher among nursing and physiotherapy students.
  • Additionally, older students and those living in urban areas demonstrated better practices toward COVID-19, although the type of training program did not significantly affect knowledge or practices.
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  • The study investigates microplastic pollution in Laguna de Bay, the largest freshwater lake in the Philippines, revealing for the first time its extent in this ecosystem.
  • A total of 100 microplastics were found across 10 sampling sites, with fibers being the most common type, and blue microplastics being notably prevalent.
  • The findings highlight the need for improved plastic waste management in areas with high population density and suggest further research into the impact of microplastics on local fisheries and aquatic resources.
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Introduction: Antimicrobial resistance (AMR) is a global public health problem that has led to increased morbidity and mortality, especially in low- and middle-income countries such as Zambia. This study evaluated AMR knowledge, attitudes and practices among pharmacy personnel and nurses at Ndola Teaching Hospital, Zambia's second-largest hospital.

Methods: A descriptive cross-sectional study was conducted among 263 participants using a structured questionnaire.

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Salmonella virulence relies on the ability of this bacterium to invade the intestinal epithelium and to replicate inside macrophages, which are functions mainly encoded in Salmonella pathogenicity islands 1 and 2 (SPI-1 and SPI-2), respectively. Complex regulatory programs control the expression of SPI-1 and SPI-2 and functionally related genes, involving the integration of ancestral regulators and regulators that Salmonella has acquired during its evolution. Interestingly, some previous studies have revealed cross talk between the regulatory programs for SPI-1 and SPI-2.

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Background: Severe neonatal jaundice can result in long term morbidities and mortality when left untreated. Phototherapy is the main-stay intervention for treating moderate jaundice and for prevention of the development of severe jaundice. However, in resource-limited health care settings, phototherapy has been inconsistently used.

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Introduction: vaccinations against COVID-19 have been instituted to contain the pandemic. However, information about the acceptability of COVID-19 vaccines in Zambia is lacking. Therefore, the study assessed the prevalence and factors associated with COVID-19 vaccine acceptance among the general population in Zambia.

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The formation of craters is an important issue in the investigations of the surface of the earth and other planets. The aim of the study was to check whether the different textures of sand beds affect the size and dynamics of the formation of craters and ejection curtain after high-velocity impacts. The experiments were conducted using an aluminium impactor at two impact speeds (~700 and ~1300 m∙s-1) and a sand bed composed of either a broad range of sizes (<2.

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Background: Human milk insufficiency is a significant barrier to implementing breastfeeding, and it is identified as a prevalent concern in 60-90% of mothers in low-and-middle-income countries. Breastmilk insufficiency can lead to hypoglycemia, hypernatremia, nutritional deficiencies, and failure to thrive in newborns and infants. Studies investigating the impact of breastfeeding interventions to improve milk production highlight inconsistencies between healthcare workers and mothers perceived support, as well as gaps in practical knowledge and training.

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Background: Exclusive breastfeeding is widely accepted as a key intervention with proven efficacy for improving newborn survival. Despite international commitments and targets to support and promote breastfeeding, there are still gaps in meeting and maintain coverage in many sub-Saharan African countries. This paper aimed to triangulate the perspectives of health workers, mothers, and their family members with facility assessments to identify gaps to improve breastfeeding support in in Malawi.

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Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disease resulting from mutations in the NTRK1 gene encoding the neurotrophic tyrosine kinase-1 receptor. In this multicenter observational retrospective study, we investigated CIPA patients identified from French laboratories sequencing the NTRK1 gene, and seven patients were identified. Patients originated from France (2), Suriname (2), Mali (1), Kazakhstan (1), and Algeria (1).

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