Neonatal atypical hemolytic uremic syndrome may cause prenatal asphyxia.

Microthrombi formation and hemolytic anemia are signs of hemolytic-uremic syndrome (HUS) that result from platelet consumption and red blood cell (RBC) destruction due to vascular damage. HUS manifests as a triad of signs: micro-angiopathic hemolytic anemia, thrombocytopenia, and uremia. Prenatal asphyxia (PA) also leads to renal insufficiency and vascular damage.