Publications by authors named "Ban K Tee"
Importance: Emerging evidence suggests that risk of bacterial sexually transmitted infections (STIs) increases among gay and bisexual men following initiation of HIV preexposure prophylaxis (PrEP).
Objective: To describe STI incidence and behavioral risk factors among a cohort of predominantly gay and bisexual men who use PrEP, and to explore changes in STI incidence following PrEP commencement.
Design, Setting, And Participants: The Pre-exposure Prophylaxis Expanded (PrEPX) Study, a multisite, open-label intervention study, was nested within the Australian Collaboration for Coordinated Enhanced Sentinel Surveillance (ACCESS) clinic network.
Article Synopsis
- PrEP (Pre-exposure prophylaxis) is a highly effective HIV prevention method using anti-retroviral therapy, specifically aimed at individuals at high risk, with the potential to reduce local HIV incidence by 25% overall and 30% among gay and bisexual men.
- The PrEPX study in Victoria, Australia intends to provide generic PrEP to 3,800 individuals over 36 months, involving regular health screenings and data collection to monitor its effectiveness and participant behavior.
- Important insights gained from this study will inform future PrEP implementation strategies and potentially influence policy regarding subsidized access to PrEP medications in Australia.
Objectives: We quantified concomitant medication polypharmacy, pharmacokinetic and pharmacodynamic interactions, adverse effects and adherence in Australian adults on effective antiretroviral therapy.
Design: Cross-sectional.
Methods: Patients recruited into a nationwide cohort and assessed for prevalence and type of concomitant medication (including polypharmacy, defined as ≥5 concomitant medications), pharmacokinetic or pharmacodynamic interactions, potential concomitant medication adverse effects and concomitant medication adherence.