Antiproliferative and Proapoptotic Activities of Marine Sponge Extract on Breast Carcinoma Cell Line (MCF-7).

Background: Marine sponge is a rich natural resource of many pharmacologically important compounds.

Objective: Marine sponge , collected from North Bay, South Andaman Sea, India, was screened for potential antiproliferative and proapoptotic properties on a breast adenocarcinoma cell line (MCF-7).

Materials And Methods: 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay was used to test the antiproliferative and cytotoxicity effects of the sponge extract.