Metastatic eccrine porocarcinoma.

Eccrine porocarcinoma (EP) is a rare malignant tumor arising from the intraepidermal sweat duct. The lesions have a varied clinical appearance and usually are asymptomatic. In reported cases, metastasis is rare but can be devastating when it occurs.

Health outcomes in atopic dermatitis.

Atopic dermatitis is a chronic inflammatory skin disease that disrupts the daily work and social lives of patients. Treatment of atopic dermatitis makes use of a variety of therapies, from medications to nutritional supplements to psychotherapy. Health outcomes research evaluates the efficacy, safety, and impact on health-related quality of life of these therapies.

Burn unit experience treating giant melanocytic nevi: 10-year review.

Giant congenital melanocytic nevi (GCMN) are rare lesions that are present in 1 in every 20,000 new births. A 10-year review of all patients treated at a pediatric burn center was performed with the goal of identifying the characteristics of patients with GCMN and the outcomes of the treatment provided in a burn center. Thirty-six patients met the definition of GCMN; 64% were female and 36% were male.

Ocular psoriasis.

Background: Psoriasis is associated with several extracutaneous manifestations of which ocular complications are common. Signs and symptoms of ocular psoriasis may be subtle and overlooked. The dermatologic literature has generally underaddressed these complications; however, a thorough understanding of ophthalmic involvement is important to the comprehensive care of patients with psoriasis.

Health outcome measures in atopic dermatitis: a systematic review of trends in disease severity and quality-of-life instruments 1985-2010.

Background: A number of disease-severity and quality-of-life (QoL) instruments have emerged in atopic dermatitis (AD) in the last decade.

Objectives: To identify trends in outcomes instruments used in AD clinical trials and to provide a useful summary of the dimensions and validation studies for the most commonly used measures.

Method: All randomized control trials (RCTs) from 1985 to 2010 in the treatment of AD were examined.

Percutaneous absorption of vapors in human skin.

Context: The absorption of vapors through the skin is an important issue because exposure of skin to chemicals in the ambient air occurs at all times. In regards to occupational health, accurately quantifying percutaneous absorption is crucial for worker health and safety.

Objective: Review the available data regarding the percutaneous absorption of vapors in humans.