[Liver damage during administration of itraconazole (Trisporal)].

Three case histories are described of patients, two women aged 62 and 57 and a man aged 75 years, who developed symptomatic hepatic injury five to six weeks after starting itraconazole treatment. In two of them the biochemical pattern of liver injury was cholestatic. Other causes of hepatic injury were excluded.

[Use of the Doppler for intrafemoral injection in arteritis].

The discovery of a femoral artery that is clinically non palpable can be made using the Doppler. It is thus possible to use a direct intra-arterial treatment. This is what was done by the authors, who thereby divided the patients into two groups: the first, 22, with non palpable femoral arteries; the second, 20, with palpable femoral arteries.

[Long-term results of the treatment of arteritis with intra-arterial injections using Reboul's technique].

We have made a non-selective search for patients undergoing treatment for more than five years for an arterial deficiency of the lower limbs. Most of the patients studied suffered from intermittent claudications for which surgical treatment was impossible (distal lesions, diabetes, coronaritis) or had failed (sympathectomy, recurrences). Faced with the inefficiency of vasodilators, and in addition to strict medical treatment of the risks factors of arterio-sclerosis disease (tobacco, obesity, hypercholesterol, sedentary habits), we treated these patients using intra-arterial injections according to the method of Reboul.

[Some little-known conservative methods of treatment of Raynaud's syndrome].

In 20 patients with Raynaud's phenomenon affecting the upper or lower limbs (1974-1976), 4 methods of conservative therapy were used, in combinations according to the case: 1) Intraarterial injections of xylocaine-priscol-pronestyl. 2) Nitroglycerine ointment. 3) More rarely, paraphalangeal injections of 1% quinine-urea.