[Experience with the parallel use of immunoenzyme analysis and copro-ovoscopy for assessing the clonorchiasis infectivity of the population of Khabarovsk Territory].

The paper describes how enzyme immunoassay (EIA) and copro-ovoscopy are concurrently used to define the spread of clonorchiasis among the population of the Nanaĭsk District in the Khabarovsk Territory. It shows the efficiency of EIA in seroepidemiological surveys and the possibility of its use in endemic areas. The sensitivity of EIA to determine antibodies to Clonorchis antigens was 70.

[The effectiveness of an immunoenzyme test with homologous and heterologous antigens in clonorchiasis].

An enzyme immunoassay with homologous and heterologous antigens has been elaborated for the diagnosis of clonorchiasis. 251 blood serum samples from patients with clonorchiasis have been studied, as well as 230 samples from patients with geohelminthiases obtained from North Vietnam provinces and 299 samples from Moscow donors. The test sensitivity and specificity were 78.

[An immunoenzyme test in the diagnosis of opisthorchiasis and in seroepidemiological research].

An indirect method for the determination of antibodies to Opisthorchis antigens has been used in the elaboration of enzyme immunoassay for opisthorchiasis diagnosis. A visual method for the assessment of the results has been suggested. Its diagnostic efficacy has been determined.

[Experimental imaginal Echinococcus multilocularis infestation of golden hamsters].

The imago stage of Echinococcus multilocularis development (prior to maturation of parasite oocysts) has been described in the intestine of golden hamsters infected by parenteral penetration of an Alveococcus agent and given hydrocortisone subcutaneously for 3 days before the infection and on the day of the infection, mean total drug dose being about 250 mg/kg. The number of helminths developed on days 8-35 of postinvasion ranged from 432 to 1863, their length was 1.0 to 4.

[Seroepidemiologic characteristics of opisthorchiasis foci with various endemic levels].

Combined coprological (by an ether-formol method) and serological (by solid-phase enzyme immunoassay--EIA) screening of the population to detect opisthorchiasis was performed in the settlements situated in the Ob, Dnieper and Northern Dvina basins. Disease rate in the hyperendemic area on the Ob exceeded 80%, by the results of coprological population screening, while annual infestation rate established on the basis of specific antibodies determination in the blood was 70%. Infestation and disease rates in mesoendemic area, at the Ob tributary and in the Dnieper basin were practically equal and accounted for 30-40%.