Congenital lymphovascular malformations with urological symptoms: a report of two cases and review of the literature.

Objectives: To collect and review the diagnostic and therapeutic solutions for primary and congenital lymphovascular malformations leading to urological symptoms in childhood and also to find the most efficient therapeutic algorithms managing such conditions.

Methods: In our work, we assemble all the diagnostic and therapeutic tools for lymphovascular malformations with urological-urogenital symptoms and demonstrate the interventional therapeutic algorithms through two of our cases where surgery (laparoscopic intervention and clipping of the lymph vessel) had to be performed to stop lymphoid leakage and restore anatomy.

Results: In cases, where lymphovascular malformations and urological-urogenital symptoms are both present, therapeutical success is graded by Browse's scoring system.

Expression of VEGF in neonatal urinary obstruction: does expression of VEGF predict hydronephrosis?

Background: In animal studies, the inhibition of VEGF activity results in high mortality and impaired renal and glomerular development. Mechanical stimuli, like mechanical stretch in respiratory and circulatory systems, results in an elevated expression of VEGF. In animal models, the experimental urinary obstruction is associated with stretching of tubular cells and activations of the renin-angiotensin system.

[Intermittent hydronephrosis in childhood].

Introduction: Intermittent pelviureteric junction obstruction, and its consequence,intermittent hydronephrosis is a difficult condition to identify. The renal collecting system is not dilated between the episodes of abdominal pain attacks and a prompt investigation is hard to carry out during the time of painful crisis. Therefore, most of the patients are initially misdiagnosed.

Long-term psychological and sexual outcomes of severe penile hypospadias repair.

Introduction: Hypospadias is the most common penis malformation, and there exist a variety of surgical approaches used to correct the abnormal position of the meatus. Although the long-term outcomes of surgery are considered important for psychosexual development, only a few attempts have been made to evaluate patient satisfaction.

Aim: The aim of our study was to evaluate surgical results and psychosocial adaptations in a homogeneous group of subjects with severe penile hypospadias who underwent the same types of surgical repairs during childhood and compare the results to data obtained from age-matched healthy controls.

Perioperative analgesia of infants during the therapy for retinopathy of prematurity.

Background: In this retrospective investigation, we compared the main anesthesiologic aspects in the preoperative, perioperative, and postoperative care of 2 different surgical methods (cryotherapy, laser coagulation) for retinopathy of prematurity.

Material/methods: A retrospective analysis of analgesia for retinopathy of prematurity was performed for a 14-year period. Infants treated from January 1994 to December 2007 were involved in the study.