Publications by authors named "Balint Javor"
Microtiter-plate-based systems are unified platforms of high-throughput experimentation (HTE). These polymeric devices are used worldwide on a daily basis-mainly in the pharmaceutical industry-for parallel syntheses, reaction optimization, various preclinical studies and high-throughput screening methods. Accordingly, laboratory automation today aims to handle these commercially available multiwell plates, making developments focused on their modifications a priority area of modern applied research.
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- The study presents a new optochemical screening method for detecting zinc (Zn) and lead (Pb) in various solutions, addressing the need for effective analysis due to their biological and environmental significance.
- A three-step microplate modification technique was developed, which involves plasma treatment, linker-docking, and photocatalytic copolymerization, enhancing the sensitivity and functionality of the microplate for sensing.
- This innovative tool can analyze over 1000 samples per hour and operates effectively with standard microplate readers, requiring only a minimal sample volume while achieving detection limits of 8.0 × 10 and 3.0 × 10 mol/L for Zn and Pb, respectively.
The reported optical resolution method was designed to support high-throughput enantioseparation of molecular building blocks obtained by automated small-scale synthetic methods. Lipophilic esters of common resolving agents were prepared and used as liquid membranes on the indifferent polymer surface of a microtiter assay. Chiral model compounds were enriched in one of the enantiomers starting from the aqueous solutions of their racemic mixture.
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