A new approach for detecting HPV DNA in cervical swabs: comparison of nucleic acid extraction with direct PCR.

Background: Almost all cases of cervical cancer are associated with persistent high-risk HPV infection. WHO prioritizes primary HPV testing for cervical cancer screening. Cervical cancer screening programs require the ability to process a large number of samples in a simple and standardized manner and obtain reliable results.

Postoperative Analgesic Efficacy of Clavipectoral Plane Block and Serratus Posterior Superior Intercostal Plane Block Combination in Clavicle Surgeries: A Report of 10 Cases.

This case series included 10 patients who underwent clavicular fracture surgery under general anesthesia. A novel analgesic approach combining 2 distinct nerve block techniques-serratus posterior superior intercostal plane block (SPSIPB) and clavipectoral plane block (CPPB)-was used for postoperative pain management. SPSIPB provided sensory blockade for the innervation of the clavicular skin, whereas CPPB targeted the clavipectoral fascia.

Absolute, not perceived, delay modulates agency judgement: Evidence for cognitive impenetrability of sense of agency.

The sense of agency, which refers to awareness of causing events, is consistently influenced by the time interval between actions and their outcomes such that longer delays diminish the perceived strength of the agency. This study investigated whether the sense of agency is modulated by the distance between experienced delays or by their subjective discriminability, which is known to be subject to Weber's law (discriminability being a function of ratios rather than absolute differences between time intervals). To this end, participants executed keypress actions leading to outcomes at varying delays.

Temporal error monitoring: Does agency matter?

Error monitoring is the ability to report one's errors without relying on feedback. Although error monitoring is investigated mostly with choice tasks, recent studies have discovered that participants parametrically also keep track of the magnitude and direction of their temporal, spatial, and numerical judgment errors. We investigated whether temporal error monitoring relies on internal generative processes that lead to the to-be-judged first-order timing performance.

Mice monitor their timing errors.

Animals often engage in representationally guided goal-directed behaviors. These behaviors are thus also subjected to representational uncertainty (e.g.

Surfacing of Latent Time Memories Supports the Representational Basis of Timing Behavior in Mice.

Animals can adapt their reward expectancy to changes in delays to reward availability. When temporal relations are altered, associative models of interval timing predict that the original time memory is lost due to the updating of the underlying associative weights, whereas the representational models render the preservation of the original time memory (as previously demonstrated in the extinction of conditioned fear). The current study presents the critical test of these theoretical accounts by training mice with two different intervals in a consecutive fashion (short → long or long → short) and then testing timing behaviors during extinction where neither temporal relation is in effect.

Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block in Modified Radical Mastectomy Surgeries: A Case Series.

Effective pain management is crucial for modified radical mastectomy (MRM) surgeries. The Serratus Posterior Superior Intercostal Plane Block (SPSIPB), introduced in 2023, shows promise for postoperative analgesia. This study was designed to demonstrate the analgesic efficacy of the SPSIPB in MRM surgeries.

Altered temporal awareness during Covid-19 pandemic.

Social isolation during the COVID-19 pandemic had profound effects on human well-being. A handful of studies have focused on how time perception was altered during the COVID-19 pandemic, while no study has tested whether temporal metacognition is also affected by the lockdown. We examined the impact of long-term social isolation during the COVID-19 pandemic on the ability to monitor errors in timing performance.

Neurocomputational Models of Interval Timing: Seeing the Forest for the Trees.

Extracting temporal regularities and relations from experience/observation is critical for organisms' adaptiveness (communication, foraging, predation, prediction) in their ecological niches. Therefore, it is not surprising that the internal clock that enables the perception of seconds-to-minutes-long intervals (interval timing) is evolutionarily well-preserved across many species of animals. This comparative claim is primarily supported by the fact that the timing behavior of many vertebrates exhibits common statistical signatures (e.

Is Serratus Posterior Superior Intercostal Plane Block a Novel Indication for the Management of Pain in Thoracic Acute Herpes Zoster? A Case Report.

Postherpetic neuralgia results from varicella-zoster virus reactivation post-chickenpox infection, manifesting as persistent and severe pain lasting a minimum of 3-mo post-herpes zoster onset. Traditional postherpetic neuralgia management comprises antiviral, analgesic medications, corticosteroids, and various agents. Ultrasound-guided nerve blocks have recently emerged as a promising postherpetic neuralgia treatment.

Memory capacity as the core mechanism of the development of space-time interferences in children.

This study investigated the development of spatiotemporal perceptual interactions in 5-to-7 years old children. Participants reproduced the temporal and spatial interval between sequentially presented visual stimuli. The time and spacing between stimuli were experimentally manipulated.

Bayes Optimal Integration of Social and Endogenous Uncertainty in Numerosity Estimation.

One of the most prominent social influences on human decision making is conformity, which is even more prominent when the perceptual information is ambiguous. The Bayes optimal solution to this problem entails weighting the relative reliability of cognitive information and perceptual signals in constructing the percept from self-sourced/endogenous and social sources, respectively. The current study investigated whether humans integrate the statistics (i.

Efficacy of Serratus Posterior Superior Intercostal Plane Block on Postoperative Pain and Total Analgesic Consumption in Patients Undergoing Reduction Mammoplasty Surgery: An Evidence Based Report.

Serratus posterior superior intercostal plane block (SPSIPB) is a novel technique that provides analgesia in shoulder, hemithorax and in the back of the neck. In this study, the efficacy of this block on postoperative pain and quality of recovery is reported in ten consecutive patients who had undergone reduction mammoplasty. Blocks were performed bilaterally with 30 ml 0.

Efficacy of serratus posterior superior intercostal plane block (SPSIPB) on post-operative pain and total analgesic consumption in patients undergoing video-assisted thoracoscopic surgery (VATS): A double-blinded randomised controlled trial.

Background And Aims: Serratus posterior superior intercostal plane block (SPSIPB) is a novel technique that can provide analgesia in the hemithorax, shoulder, and back of the neck. This study aimed to evaluate the post-operative analgesic effect of SPSIPB in patients undergoing video-assisted thoracoscopic surgery (VATS).

Methods: It is a double-blind, randomised controlled trial.

Effects of Modified Thoracoabdominal Nerve Block Through Perichondrial Approach on Postoperative Pain and Analgaesic Consumption in Patients Undergoing Laparoscopic Cholecystectomy.

Objective: To investigate postoperative analgaesic efficacy of modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) and its effect on opioid consumption in patients undergoing laparoscopic cholecystectomy (LC) surgery.

Study Design: Randomised, controlled trial. Place and Duration of the Study: Department of Anaesthesiology and Reanimation, Sivas Cumhuriyet University, Sivas, Turkiye, from April to May 2023.

Metric error monitoring as a component of metacognitive processing.

Metacognitive processing constitutes one of the contemporary target domains in consciousness research. Error monitoring (the ability to correctly report one's own errors without feedback) is considered one of the functional outcomes of metacognitive processing. Error monitoring is traditionally investigated as part of categorical decisions where choice accuracy is a binary construct (choice is either correct or incorrect).

Use of follow-on fingolimod for multiple sclerosis: Analysis of effectiveness and patient reported outcomes in a real-world clinical setting.

Background: Follow-on disease modifying therapies (FO-DMTs) do not always require Phase III studies. There are concerns that cheaper FO-DMTs are only used to reduce healthcare costs. However, the well-being of people with MS (pwMS) should be a priority.

Temporal Error Monitoring Does Not Depend on Working Memory.

Working memory (WM) and metacognition has been documented to be in a reciprocal relationship. This study aims to address if temporal error monitoring performance can be diminished with increased working memory load. We hypothesized that if temporal error monitoring has commonalities with perceptual error monitoring, temporal error monitoring performance should be diminished by increased working memory load.

Working memory for time intervals: Another manifestation of the central tendency effect.

The relationship between working memory and time perception has been typically investigated using dual-task paradigms (e.g., testing timing performance during a concurrent task).

Dynamics of retrospective timing: A big data approach.

Most interval timing research has focused on prospective timing tasks, in which participants are explicitly asked to pay attention to time as they are tested over multiple trials. Our current understanding of interval timing primarily relies on prospective timing. However, most real-life temporal judgments are made without knowing beforehand that the durations of events will need to be estimated (i.

The Relationship of Evidence-Based Nursing Attitudes of Nurses Working in Surgical Wards With Patient-Centered Care Competencies.

Purpose: The aim of this study was to determine the relationship between the evidence-based nursing attitudes of nurses working in surgical wards and their patient-centered care competencies.

Design: This was a prospective, correlational, and cross-sectional study.

Methods: The sample for this study included 209 surgical nurses working in the surgical clinics of a research hospital.