Publications by authors named "Balazs Thurzo"
Article Synopsis
- Alzheimer's disease is increasingly affecting aging societies and primarily appears in a sporadic form linked to various genetic and environmental factors.
- The condition can be viewed as an intensified version of the natural aging process of the brain, marked by the buildup of amyloid plaques due to impaired amyloid elimination.
- The review focuses on the role of specific neuropeptides in accelerating dementia and explores their potential as therapeutic targets to slow down disease progression.
The orexin/hypocretin neuropeptide family has emerged as a focal point of neuroscientific research following the discovery that this family plays a crucial role in a variety of physiological and behavioral processes. These neuropeptides serve as powerful neuromodulators, intricately shaping autonomic, endocrine, and behavioral responses across species. Notably, they serve as master regulators of vigilance and stress responses; however, their roles in food intake, metabolism, and thermoregulation appear complementary and warrant further investigation.
View Article and Find Full Text PDFThe actions of neuropeptide AF (NPAF), on the hypothalamic-pituitary-adrenal (HPA) axis, behavior and autonomic functions were investigated. NPAF (0.25, 0.
View Article and Find Full Text PDFThe present experiments focused on the effects of neuromedin S on hypothalamic-pituitary-adrenal (HPA) activation and behavior. The peptide (0.25-1 nmol) was administered intracerebroventricularly to rats, the behavior of which was monitored by means of telemetry, open field observations and an elevated plus-maze (EPM) test.
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