Outcome comparison of primary trapeziectomy versus secondary trapeziectomy following failed total trapeziometacarpal joint replacement.

Purpose: To compare the clinical outcome between secondary trapezial excision after failed total trapeziometacarpal joint replacement and primary trapeziectomy.

Methods: Between October 2003 and July 2008, we performed 16 revision procedures in our institution because of failed trapeziometacarpal joint replacements. Of these patients, 15 were followed up.

Enhanced early tissue regeneration after matrix-assisted autologous mesenchymal stem cell transplantation in full thickness chondral defects in a minipig model.

Adult mesenchymal stem cells (MSCs) are an attractive cell source for new treatment strategies in regenerative medicine. This study investigated the potential effect of matrix assisted MSC transplantation for articular cartilage regeneration in a large-animal model 8 weeks postoperatively. MSCs from bone marrow aspirates of eight Goettingen minipigs were isolated and expanded prior to surgery.