Intelligent Modeling and Multi-Response Optimization of AWJC on Fiber Intermetallic Laminates through a Hybrid ANFIS-Salp Swarm Algorithm.

The attainment of intricate part profiles for composite laminates for end-use applications is one of the tedious tasks carried out through conventional machining processes. Therefore, the present work emphasized hybrid intelligent modeling and multi-response optimization of abrasive waterjet cutting (AWJC) of a novel fiber intermetallic laminate (FIL) fabricated through carbon/aramid fiber, reinforced with varying wt% of reduced graphene oxide (r-GO) filled epoxy resin and Nitinol shape memory alloy as the skin material. The AWJC experiments were performed by varying the wt% of r-GO (0, 1, and 2%), traverse speed (400, 500, and 600 mm/min), waterjet pressure (200, 250, and 300 MPa), and stand-off distance (2, 3, and 4 mm) as the input parameters, whereas kerf taper () and surface roughness () were considered as the quality responses.

Optimal energy efficient path planning of UAV using hybrid MACO-MEA* algorithm: theoretical and experimental approach.

Autonomous mission capabilities with optimal path are stringent requirements for Unmanned Aerial Vehicle (UAV) navigation in diverse applications. The proposed research framework is to identify an energy-efficient optimal path to achieve the designated missions for the navigation of UAVs in various constrained and denser obstacle prone regions. Hence, the present work is aimed to develop an optimal energy-efficient path planning algorithm through combining well known modified ant colony optimization algorithm (MACO) and a variant of A*, namely the memory-efficient A* algorithm (MEA*) for avoiding the obstacles in three dimensional (3D) environment and arrive at an optimal path with minimal energy consumption.

A Hybrid Approach of ANFIS-Artificial Bee Colony Algorithm for Intelligent Modeling and Optimization of Plasma Arc Cutting on Monel™ 400 Alloy.

This paper focusses on a hybrid approach based on genetic algorithm (GA) and an adaptive neuro fuzzy inference system (ANFIS) for modeling the correlation between plasma arc cutting (PAC) parameters and the response characteristics of machined Monel 400 alloy sheets. PAC experiments are performed based on box-behnken design methodology by considering cutting speed, gas pressure, arc current, and stand-off distance as input parameters, and surface roughness (Ra), kerf width (kw), and micro hardness (mh) as response characteristics. GA is efficaciously utilized as the training algorithm to optimize the ANFIS parameters.

Renal mitochondria can withstand hypoxic/ischemic injury secondary to renal failure in uremic rats pretreated with sodium thiosulfate.

Background: Sodium thiosulfate (STS) is a potent drug used to treat calcific uremic arteriopathy in dialysis patients and its mode of action is envisaged by calcium chelation and antioxidant potential. STS's action on mitochondrial dysfunction, one of the major players in the pathology of vascular calcification is yet to be explored.

Methods: Adenine (0.

Profunda Femoris Pseudoaneurysm following Total Hip Arthroplasty Revision.

Vascular injuries following total hip arthroplasty (THA) are very rare, with pseudoaneurysm being a small subset. We report a case of profunda femoris artery (PFA) pseudoaneurysm in a 61-year-old male following a posterior approach revision left THA. Presentation involved continued blood transfusion requirements several weeks postoperatively.

Tibiofemoral Osteoarthritis After Surgical or Nonsurgical Treatment of Anterior Cruciate Ligament Rupture: A Systematic Review.

Objective:   To determine if surgical or nonsurgical treatment of anterior cruciate ligament rupture affects the prevalence of posttraumatic tibiofemoral osteoarthritis (OA).

Data Sources:   Studies published between 1983 and April 2012 were identified via EBSCOhost and OVID. Reference lists were then screened in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.

Saline-assisted aspirations for collecting synovial fluid from noneffused knees: technique and validation.

Context: To better understand why a knee develops osteoarthritis after joint trauma we need to assess the local biochemical changes. Unfortunately, it is challenging to obtain synovial fluid from a knee with no effusion.

Objective: To describe the authors' protocol for aspirating synovial fluid from noneffused knees.

Medication and supplement use for managing joint symptoms among patients with knee and hip osteoarthritis: a cross-sectional study.

Background: The purpose was to determine the professionally-guided and self-guided medication and supplement use for joint symptom management among patients with knee and/or hip osteoarthritis (OA) in an urban hospital-based outpatient orthopedic practice.

Methods: The study design was cross-sectional. Patients diagnosed by radiographs and clinical symptoms with knee and/or hip OA were recruited from an inner-city hospital-based outpatient orthopaedic office.

Biochemical comparison of osteoarthritic knees with and without effusion.

Background: Several symptom-relieving interventions have been shown to be efficacious among osteoarthritis (OA) patients with knee effusion; however, not every symptomatic knee OA patient has clinical effusion. Results may be over-generalized since it is unclear if effused knees represent a unique pathological condition or subset compared to knees without effusion. The primary purpose of this study was to determine if biochemical differences existed between OA knees with and without effusion.

The potential of multiple synovial-fluid protein-concentration analyses in the assessment of knee osteoarthritis.

Context: Joint trauma is a risk factor for osteoarthritis (OA), which is becoming an increasingly important orthopedic concern for athletes and nonathletes alike. For advances in OA prevention, diagnosis, and treatment to occur, a greater understanding of the biochemical environment of the affected joint is needed.

Objective: To demonstrate the potential of a biochemical technique to enhance our understanding of and diagnostic capabilities for osteoarthritis.

Is osteoarthritis a heterogeneous disease that can be stratified into subsets?

Osteoarthritis is a heterogeneous disease characterized by variable clinical features, biochemical/genetic characteristics, and responses to treatments. To optimize palliative effects of current treatments and develop efficacious disease-modifying interventions, treatments may need to be tailored to the individual or a subset of osteoarthritic joints. The purpose of this review is to explore the current literature on the clinical and physiological variability in osteoarthritis and potential for stratifying patients.

Somatosensory evoked potentials as an aid in the diagnosis and intraoperative management of spinal stenosis.

The use of somatosensory evoked potentials (SEPs) in localizing the level, extent, and laterality of nerve root entrapment is clinically important. In patients with lumbar spinal stenosis, this is especially true. This study defines a prospective investigation of 20 patients with preoperative SEPs of which 11 patients had intraoperative SEPs correlated with their computed tomographic (CT) scan and/or myelographic findings.