Peracetylation transforms natural products beyond mere derivatization.

Peracetylation of the methanolic extract of led to the isolation of a compound with a peracetylated hex-4-en-3-one backbone. Mechanistic insights revealed that the isolated compound is an outcome of the chemical transformation of a α-dicarbonyl compound.

Artifacts from the methanolic extract of Linn.

Two new lactones, γ-butyrolactone and δ-valerolactone were isolated from the methanolic extract of . Structure elucidation was carried out by exhaustive 2D NMR analysis. The structures of the lactones depict the outcome of their isolation as a situation that involve the formation of artifacts.

A pentacarbomethoxycyclopentadiene (PCCP) organic Brønsted acid catalyzed stereoselective glycosidation of N-pentenyl orthoesters (NPOE) of d-glucose and d-galactose, in conjunction with N-iodosuccinimide.

Herein, we report our preliminary results in utilizing the organic Brønsted acid, pentacarbomethoxycyclopentadiene (PCCP), for catalysing the glycosidation with n-pentenyl orthoesters (NPOE) of d-glucose and d-galactose in the presence of N-iodosuccinimide (NIS). Benzoyl and benzyl protection in d-glucosyl NPOEs led to 1,2-trans glycosides, while acetyl protection in NPOE led to a mixture of 1,2-cis and trans glycosides with >75% cis selectivity, and d-galactosyl NPOEs led to 1,2-orthoesters. Substrate scope was demonstrated with acceptors of natural product relevance.