Publications by authors named "Balaji V"

Background: Streptococcus dysgalactiae subsp equisimilis (SDSE) is an emerging pathogen causing pharyngitis and post-streptococcal sequelae like S. pyogenes. SDSE was initially considered a commensal microorganism inhabiting the upper respiratory tract and skin.

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  • Chronic Limb Threatening Ischemia (CLTI) is a severe condition leading to high rates of limb amputation and cardiovascular death, particularly in cases where standard treatments fail.
  • Endovascular interventions are the main treatment strategy, but a significant number of patients are considered "no-option," prompting interest in new therapies like bone marrow-derived mesenchymal stromal cells (BM-MSC).
  • REGENACIP is an approved BM-MSC therapy in India for patients with critical limb ischemia who are not candidates for traditional revascularization, and this review discusses its potential benefits and effectiveness in treating CLTI.
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The spread of carbapenemase-producing gram-negative pathogens, especially those producing metallo-β-lactamases (MBLs), has become a major health concern. MBLs are molecularly the most diverse carbapenemases, produced by a wide spectrum of gram-negative organisms, including the Enterobacterales, Pseudomonas spp., Acinetobacter baumannii, and Stenotrophomonas maltophilia, and can hydrolyze most β-lactams using metal ion cofactors in their active sites.

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  • The study investigates the prevalence and impact of candidaemia in 67 ICUs across India, assessing how the COVID-19 pandemic influenced its rates and mortality.* -
  • Data from 401,601 patient days revealed higher candidaemia rates in COVID-19 ICUs (2.52/1000 patient days) compared to non-COVID-19 ICUs (1.05/1000 patient days), with associated mortality significantly higher in COVID-19 cases (61% vs. 41%).* -
  • Analysis identified C. tropicalis as the most common isolated species (26.7%), while C. auris, which had a high mortality rate, accounted for 17.5% of isolates
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Rationale: This case report presents a rare combination of congenital anomalies in an otherwise healthy male infant born at 36 weeks. The infant was diagnosed with congenital maxillomandibular synechia, ectrodactyly, and ankyloglossia superior syndrome (ASS).

Patient Concerns: Inability to open the mouth completely, feeding challenges, and a cleft palate.

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Pregnancy is accompanied by several physiological changes such as altered salivary flow rate, mucosal immunity and altered microbial flora. This may predispose pregnant women to oral health problems. This could be accentuated by oral health neglect, polypharmacy and a host of other factors, including dietary modification.

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A novel concept of developing multi-principal elements, or compositional complex alloys is referred as high-entropy alloys (HEAs). This review addresses the role of entropy in alloying additions along with the effect of various elements listed in the periodic table in forming the HEAs. Phase formation rules and the associated parameters along with their significance are discussed.

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  • - Plant diseases are increasingly common and cause significant economic losses, prompting the use of IoT technology for better identification and management in agriculture.
  • - A new model utilizes IoT for precise plant disease detection, starting from image collection, encryption via AES, to image processing using Mask R-CNN for segmentation.
  • - The detection phase employs an advanced hybrid network (ADHCN-AM), achieving a 95% improvement in effectiveness compared to previous methods, measured by the Matthews Correlation Coefficient (MCC).
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  • Multidrug-resistant (MDR) pathogens are a significant global health threat, particularly from food- and water-borne sources, necessitating new countermeasures like phage therapy.
  • Researchers isolated and characterized two specific phages from environmental water samples that showed strong lytic activity against certain MDR strains and had favorable stability and absorption characteristics.
  • These phages, with distinct genomic profiles, demonstrated potential effectiveness in reducing viable counts of MDR pathogens in raw chicken, suggesting their application in treating shigellosis and controlling MDR bacteria in food storage.
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Background: Left atrial volume index (LAVI) is one marker of atrial myopathy, which is increasingly being recognized as a cause of cardioembolic stroke even in the absence of atrial fibrillation. Cardiac embolism is associated with larger strokes than other stroke mechanisms. The purpose of this study was to examine the association between LAVI and total brain infarct volume in patients with ischemic stroke.

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Nuclear medicine imaging modalities such as PET and SPECT are confounded by high noise levels and low spatial resolution, necessitating postreconstruction image enhancement to improve their quality and quantitative accuracy. Artificial intelligence (AI) models such as convolutional neural networks, U-Nets, and generative adversarial networks have shown promising outcomes in enhancing PET and SPECT images. This review article presents a comprehensive survey of state-of-the-art AI methods for PET and SPECT image enhancement and seeks to identify emerging trends in this field.

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Background: Horadandia brittani is a small cyprinid fish species initially discovered in the coastal floodplains of southern India. For almost 50 years, the genus Horadandia was monotypic with a single species confined to Sri Lanka. In 1992, a new species H.

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Rationale: SAMS syndrome is a rare genetic disorder characterized by midline facial clefting, skeletal anomalies, and other defects.

Salient Features: Among the craniofacial manifestations of SAMS syndrome is the presence of a median mandibular cleft (MMC). MMC is a rare occurrence and in this syndrome, it poses a complex challenge for both functional and aesthetic reasons.

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  • Environmental surveillance (ES) for Salmonella Typhi is a cost-effective way to identify communities at risk for typhoid fever by utilizing standardized protocols for sample collection and analysis.
  • A study conducted in Vellore, India and Blantyre, Malawi showed significantly higher S. Typhi presence in Vellore samples, despite low reported clinical cases of typhoid during the study period.
  • The findings suggest that ES can effectively indicate the prevalence of S. Typhi even without clinical cases, which may help guide future public health actions, such as vaccine distribution.
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Background Inguinal hernia is one of the most common conditions in India, and history has many repair techniques recorded in it. Postoperative pain still remains a problem despite tension-free hernioplasty being accepted as the gold standard. Increased duration of surgery not only exposes the patient to unwanted increased chances of mesh infection but also reduces the surgeon's productivity if continued persistently.

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Background: To assess the reasons for dental implant failures.

Materials And Methods: A total of 100 implants were studied in 80 subjects. The radiographic investigations were performed to assess the record length of implant and diameter of implant.

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Background: Typhoid fever causes nearly 110,000 deaths among 9.24 million cases globally and disproportionately affects developing countries. As a control measure in such regions, typhoid conjugate vaccines (TCVs) are recommended by the World Health Organization (WHO).

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  • The classification of neuronal subpopulations has improved, but their impact on behavior is still unclear.
  • This study focuses on the flocculus in the cerebellum and discovers distinct subpopulations of Purkinje cells that have varying properties and play unique roles in movement.
  • Optogenetic stimulation shows that these Purkinje cells generate movements around the same axis but with different movement characteristics, indicating they work in separate circuits to influence specific movement parameters.
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We present a case of post-trabeculectomy encapsulated dysesthetic bleb with scleral fistula, managed successfully with autograft. The child was operated on twice before for trabeculectomy, and intraocular pressure (IOP) recorded was in the normal range for the initial few years. This time child presented with a large encapsulated dysesthetic bleb with borderline IOP.

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Transferring of data in machine learning from one party to another party is one of the issues that has been in existence since the development of technology. Health care data collection using machine learning techniques can lead to privacy issues which cause disturbances among the parties and reduces the possibility to work with either of the parties. Since centralized way of information transfer between two parties can be limited and risky as they are connected using machine learning, this factor motivated us to use the decentralized way where there is no connection but model transfer between both parties will be in process through a federated way.

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Rice () is India's major crop. India has the most land dedicated to rice agriculture, which includes both brown and white rice. Rice cultivation creates jobs and contributes significantly to the stability of the gross domestic product (GDP).

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Hfq, RNA binding protein, is widely found in most of the prokaryotes. It plays a key role in gene regulation by binding with small RNA and facilitates mRNA pairing there by suppress or boost translation according to RNA structures. Interaction between sRNAs and HfQ in Salmonella SL1344 were screened using Co-Immuno Precipitation (HfQ-CoIP) studies earlier.

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