Calcified Pseudoneoplasm of the Neuraxis (CAPNON)-A Rare Cause for Temporal Lobe Epilepsy: Not all Warrant a Surgical Intervention.

Epilepsy is a common neurological condition with varied etiological causes, with temporal lobe epilepsy being the most common. Among the varied etiologies of temporal lobe epilepsy, mesial temporal sclerosis is an important one and it presents as intractable epilepsy. However, we describe here a case of intractable temporal lobe epilepsy with a rather rare etiology, calcifying pseudo neoplasm of neuraxis (CAPNON) syndrome.

Orphan disease: Cherubism, optic atrophy, and short stature.

A 12-year-old female presented with complaints of progressive visual impairment in both her eyes. On clinical examination, she was short for her age and her ophthalmoscopic examination revealed bilateral optic atrophy. Computed tomography of the patient revealed multiple expansile lytic lesions of mandible suggesting cherubism.

Comparison of post-contrast 3D-T-MPRAGE, 3D-T-SPACE and 3D-T-FLAIR MR images in evaluation of meningeal abnormalities at 3-T MRI.

Objective: This study was to assess the usefulness of newer three-dimensional (3D)-T sampling perfection with application optimized contrast using different flip-angle evolutions (SPACE) and 3D-T fluid-attenuated inversion recovery (FLAIR) sequences in evaluation of meningeal abnormalities.

Methods: 78 patients who presented with high suspicion of meningeal abnormalities were evaluated using post-contrast 3D-T-FLAIR, 3D-T magnetization-prepared rapid gradient-echo (MPRAGE) and 3D-T-SPACE sequences. The images were evaluated independently by two radiologists for cortical gyral, sulcal space, basal cisterns and dural enhancement.