Successful Endoscopic Management of Complete Tracheal Occlusion in a Child.

Prolonged mechanical ventilation following cardiopulmonary and neurological events oftentimes necessitates a tracheostomy and tracheal granulation is one of its most common late complications. The literature recommends that large granulation be managed through surgical excision or endoluminal techniques. A 6-year-old boy presented with high-grade tracheal stenosis secondary to endotracheal cuff-related injury and prolonged tracheostomy.

Prostate Metastasis in Oral Malignant Melanoma - A Case Report.

Melanoma is the ninth most prevalent and the second most lethal tumour. The aetiology and pathogenesis remain uncertain. It occurs in elderly people, over the fifth decade, and is predominant in males.

AR-UNet: A Deformable Image Registration Network with Cyclic Training.

Deformable image registration is a process to determine the non-linear spatial correspondence among deformed image pairs. Generative registration network is a novel structure involving a generative registration network and a discriminative network that encourages the former to generate better results. We propose an Attention Residual UNet (AR-UNet) to estimate the complicated deformation field.

Herpes Zoster: A Case Report of a Rare Ramification Leading to Secondary Infection.

The herpes virus causes herpes zoster (HZ) (shingles). It develops years later in elderly patients who were affected by the varicella-zoster virus in their childhood. The virus gets reactivated and typically localizes its symptoms to a particular dermatome.

ACT-R based human digital twin to enhance operators' performance in process industries.

To ensure safe and efficient operation, operators in process industries have to make timely decisions based on time-varying information. A holistic assessment of operators' performance is, therefore, challenging. Current approaches to operator performance assessment are subjective and ignore operators' cognitive behavior.

An Adaptive Kernels Layer for Deep Neural Networks Based on Spectral Analysis for Image Applications.

As the pixel resolution of imaging equipment has grown larger, the images' sizes and the number of pixels used to represent objects in images have increased accordingly, exposing an issue when dealing with larger images using the traditional deep learning models and methods, as they typically employ mechanisms such as increasing the models' depth, which, while suitable for applications that have to be spatially invariant, such as image classification, causes issues for applications that relies on the location of the different features within the images such as object localization and change detection. This paper proposes an adaptive convolutional kernels layer () as an architecture that adjusts dynamically to images' sizes in order to extract comparable spectral information from images of different sizes, improving the features' spatial resolution without sacrificing the local receptive field () for various image applications, specifically those that are sensitive to objects and features locations, using the definition of Fourier transform and the relation between spectral analysis and convolution kernels. The proposed method is then tested using a Monte Carlo simulation to evaluate its performance in spectral information coverage across images of various sizes, validating its ability to maintain coverage of a ratio of the spectral domain with a variation of around 20% of the desired coverage ratio.

Utility of Transbronchial Cryobiopsy via Flexible Bronchoscope in Diagnosis of Isolated Pulmonary LCH: A Case Report.

Flexible bronchoscopes are increasingly being used in diagnostic and therapeutic medicine and have obviated the need for and risks associated with general anesthesia. Here the authors present the case of a 2-y-old girl who was diagnosed with isolated pulmonary Langerhans cell histiocytosis by histopathology; a lung biopsy sample was obtained using a cryoprobe via a flexible bronchoscope. The girl was brought in with complaints of loss of weight, appetite loss, and rapid breathing for the past 2 mo.

Efficient design and analysis of secure CMOS logic through logic encryption.

Untrusted third parties and untrustworthy foundries highlighted the significance of hardware security in the present-day world. Because of the globalization of integrated circuit (IC) design flow in the semiconductor industry, hardware security issues must be taken to prevent intellectual property (IP) piracy. Logic encryption is an efficient method to protect circuits from IP piracy, reverse engineering, and malicious tampering of IC for Trojan insertion.

Etiology of Hemoptysis in Children and Adolescents - Multicentric Retrospective Data (2012-2021) From Chennai.

Objective: To analyze the etiology of hemoptysis in children and to correlate the severity of bleed with the etiology.

Methods: This retrospective multicentre study reviewed data from inpatient units of four tertiary care public and private sector pediatric hospitals in Tamil Nadu. Methods: Inpatient case records of children (aged 2 month-15 years) treated for hemoptysis at the four institutions between April, 2012 and March, 2021 were identified, after ethical clearance from respective institutions.

White rice, brown rice and the risk of type 2 diabetes: a systematic review and meta-analysis.

Objective: Intake of white rice has been associated with elevated risk for type 2 diabetes (T2D), while studies on brown rice are conflicting. To inform dietary guidance, we synthesised the evidence on white rice and brown rice with T2D risk.

Design: Systematic review and meta-analysis.

Tracheobronchopathia osteochondroplastica: A rare case of misdiagnosis and difficult intubation.

Tracheobronchopathia osteochondro-plastica (TPO) is a rare disorder of yet unknown etiology. The common clinical features include cough with expectoration, breathing difficulty, hemoptysis, and recurrent airway infections, which can lead to a misdiagnosis as another chronic respiratory illness in a large number of cases due to the rare nature of TPO. Here we present a 25-year-old lady who was misdiagnosed as bronchial asthma for many years, and was found to have TPO after difficulty in intubation for administering general anesthesia prior to a surgical procedure.

Caregivers' Preferences of COVID-19 Vaccination for Children: A Cross-sectional Study From Rural South India.

Objective: This study aimed to document caregivers' perceptions and preferences regarding coronavirus disease-19 (COVID-19) vaccination among children.

Methods: This cross-sectional study analyzed 272 caregivers with 347 children (aged 1-18 years) attending a subdistrict rural hospital in February-March 2022.

Results: Vaccine acceptance was high (93.

Novel daidzein molecules exhibited anti-prostate cancer activity through nuclear receptor ERβ modulation, and studies.

Eight novel ERβ selective daidzein analogues (NCE1-8) were synthesized and their anti-cancer activity was evaluated by and methods. Cytotoxicity study, Receptor binding studies, Luciferase assay, cMYC & Cyclin D1 expression and Caspase 3, 8 & 9 activities were measured to ascertain the anticancer activity and mechanism. Uterotropic, anti-androgenic and anti-tumour activities were performed in rodents.

Clinical outcomes of suspected Catheter Related Blood Stream Infection at a tertiary care center in south India.

Background: Catheter related blood stream infection (CRBSI) makes up a significant proportion of Hospital acquired infection and increases the morbidity and mortality of those affected.

Aims And Objectives: Primary aim was to study the clinical outcomes of patients with suspected Catheter Related Blood Stream Infection (CRBSI).

Results: Of the 150 participants suspected of having CRBSI, 100(67%) had CRBSI, 26(16%) patients were colonizers and 24(17%) patients had BSI from another source.

An Investigation of Rotary Drone HERM Line Spectrum under Manoeuvering Conditions.

Detecting and identifying drones is of great interest due to the proliferation of highly manoeuverable drones with on-board sensors of increasing sensing capabilities. In this paper, we investigate the use of radars for tackling this problem. In particular, we focus on the problem of detecting rotary drones and distinguishing between single-propeller and multi-propeller drones using a micro-Doppler analysis.

Acceptability and outcomes of foreskin preservation for phimosis: An Indian perspective.

Aim: Understanding the Indian perspective, effectiveness, and acceptability of prepuce conservation in children with phimosis. Circumcision is performed and recommended far too often for nonphysiological phimosis. Will a less radical approach be acceptable in the subcontinent?

Method: A two-arm study with the first arm as KAP (knowledge, attitude, and practice) study ( = 502).

Mature Cystic Teratoma of Renal Pelvis: An Unusual Presentation at an Uncommon Site.

Teratoma of the kidney is uncommon. We report a case of a young boy with a large, right-sided retroperitoneal cyst suspected as lymphangioma causing hydronephrosis. His renal pelvis was dilated, containing purulent fluid, and a nephrectomy was performed.

Gestational Diabetes Mellitus Postpartum Follow-Up Testing: Challenges and Solutions.

One in every 4 pregnancies is affected by hyperglycemia, of which 90% is gestational diabetes mellitus (GDM). Women with GDM are at a high risk of developing both short- and long-term complications. Various studies have shown the heightened risk of type 2 diabetes among women with GDM.

In silico study directed towards identification of novel high-affinity inhibitors targeting an oncogenic protein: BRD4-BD1.

Bromodomain-containing protein 4 (BRD4) is a member of the bromodomain and extra-terminal domain (BET) family of proteins. It epigentically regulates the transcription of growth-promoting genes and has become an attractive target for the development of anticancer and anti-inflammatory agents. In the current study, we performed an in silico screening of a small-molecule chemical library against the acetyl-lysine binding site of the first bromodomain (BD1) in BRD4 protein.

Phytochemical analysis and broad spectrum antimicrobial activity of ethanolic extract of Hance leaves and its solventpartitioned fractions.

Hance (yellow jasmine, Family Oleaceae) belongs to an important subclass of family whose biological significance is under explored. The current study pertains to isolation of various solvent extracts fractions and their anti-bacterial effects on the Gram-positive and Gram-negative bacterial pathogens. Ethanolic extract of Hance leaves was subjected to further partitioning using different solvents with increasing polarity to get different solvent fractions.

Emu: Engagement Modeling for User Studies.

Mobile technologies that drive just-in-time ecological momentary assessments and interventions provide an unprecedented view into user behaviors and opportunities to manage chronic conditions. The success of these methods rely on engaging the user at the appropriate moment, so as to maximize questionnaire and task completion rates. However, mobile operating systems provide little support to precisely specify the contextual conditions in which to notify and engage the user, and study designers often lack the expertise to build context-aware software themselves.

Soy isoflavones exert beneficial effects on letrozole-induced rat polycystic ovary syndrome (PCOS) model through anti-androgenic mechanism.

Context: Soy is the main source of phytoestrogens, which has long been used as traditional food. One major subtype of phytoestrogens includes isoflavones and they are scientifically validated for their beneficial actions on many hormone-dependent conditions.

Objective: The present study examines the effect of soy isoflavones on letrozole-induced polycystic ovary syndrome (PCOS) rat model.