Synopsis of recent research by authors named "Bala Umashankar"
- Bala Umashankar's recent research focuses on the molecular mechanisms underlying health complications in Cystic Fibrosis (CF), particularly the relationship between CF-related diabetes (CFRD), CFTR protein functionality, oxidative stress, and unfolded protein responses, highlighting the intricacies of pancreatic damage and endocrine dysfunction in conjunction with CF.
- His studies address the effects of chronic hypoxia on airway epithelial cells, revealing significant impacts on gene expression related to CFTR, thereby contributing to a better understanding of respiratory diseases associated with hypoxic conditions.
- Umashankar has also explored innovative therapeutic strategies for cancer, including the development of aryl-urea fatty acids that target specific cellular pathways to inhibit the migration and invasion of breast cancer cells, emphasizing the potential of dietary fats in cancer treatment.