Publications by authors named "Bala J"

Background & Objective: Placenta provides nutrition and protection from various infections and toxins to the baby while they are in the mother's womb. The present study was done to see the effects of coronavirus infection on the placenta of infected mothers and the final pregnancy outcome.

Methods: A total of 50 antenatal women (25 infected with coronavirus and 25 uninfected women) were enrolled and their placentae were examined for any significant histopathological changes.

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Purpose: The Democratic Republic of Congo has one of the highest burdens of malaria in the world, accounting for 12.3% of malaria cases and 11.6% of malaria deaths.

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Objectives: To understand the extent to which various demographic and social determinants predict mental health status and their relative hierarchy of predictive power in order to prioritise and develop population-based preventative approaches.

Design: Cross-sectional analysis of survey data.

Setting: Internet-based survey from 32 countries across North America, Europe, Latin America, Middle East and North Africa, Sub-Saharan Africa, South Asia and Australia, collected between April 2020 and December 2021.

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Over the past 30 years there have been numerous large-scale and longitudinal psychiatric research efforts to improve our understanding and treatment of mental health conditions. However, despite the huge effort by the research community and considerable funding, we still lack a causal understanding of most mental health disorders. Consequently, the majority of psychiatric diagnosis and treatment still operates at the level of symptomatic experience, rather than measuring or addressing root causes.

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The emergence of bone tissue engineering as a trend in regenerative medicine is forcing scientists to create highly functional materials and scaffold construction techniques. Bone tissue engineering uses 3D bio-printed scaffolds that allow and stimulate the attachment and proliferation of osteoinductive cells on their surfaces. Bone grafting is necessary to expedite the patient's condition because the natural healing process of bones is slow.

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Article Synopsis
  • Carbon-tetrachloride (CCl) is known to cause liver damage due to oxidative stress, while nerol is a beneficial monoterpene with antioxidant and anti-inflammatory properties.
  • The study involved 35 male rats, with one group being treated with CCl and the other groups receiving various doses of nerol to assess its protective effects against liver injury.
  • Results showed that nerol significantly improved liver function and antioxidant levels in rats exposed to CCl, suggesting it may protect the liver from oxidative stress-related damage.
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Objectives: The objective of this study is to address issues faced by doctors working in the COVID-19 units during the second phase of COVID-19 in the Czech Republic, when the country registered the highest per capita rate of new COVID-19 cases in the world.

Methods: A prospective study was designed using Google online questionnaire. Inclusion criteria were doctors from medical and surgical specialties working in COVID-19 units.

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Background: Attention-deficit hyperactivity disorder (ADHD) affects around 1 in 20 children and is associated with life-long sequelae. Previous studies of the association between Apgar score and ADHD have reported inconsistent findings.

Methods: Record linkage of maternity, prescribing and school pupil census databases was used to conduct a population e-cohort study of singleton children born in Scotland and attending school in Scotland at any point between 2009 and 2013.

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Reports suggest non-falciparum species are an underappreciated cause of malaria in sub-Saharan Africa but their epidemiology is ill-defined, particularly in highly malaria-endemic regions. We estimated incidence and prevalence of PCR-confirmed non-falciparum and Plasmodium falciparum malaria infections within a longitudinal study conducted in Kinshasa, Democratic Republic of Congo (DRC) between 2015-2017. Children and adults were sampled at biannual household surveys and routine clinic visits.

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  • Non-falciparum malaria species are increasingly recognized as significant contributors to malaria cases in sub-Saharan Africa, particularly in the Democratic Republic of Congo (DRC), which has a high incidence of malaria.
  • A longitudinal study in Kinshasa Province (2015-2017) found that the incidence of non-falciparum species was 11% for Plasmodium vivax and 7% for Plasmodium ovale within one year, while the incidence for Plasmodium falciparum was significantly higher at 67%.
  • Non-falciparum infections were more common in rural areas and among school-age children, and while there were some associations with anemia, they weren't consistent, indicating that
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Petroleum contamination constitutes a frequent incidence in various petroleum depots in Nigeria. In this study, the polycyclic aromatic hydrocarbons (PAHs) present in soil and water in communities around Petroleum Products Marketing Company (PPMC) Suleja, Nigeria, were evaluated and degraded using indigenous microorganisms. The samples sites were divided into 7 plots from where samples of water and soil were obtained: one within the PPMC depot, five from communities surrounding the depot, and the control 93,000 km from the depot.

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Background: Both diabetes mellitus and psychiatric morbidities are widely prevalent diseases which show a discerning upward trend globally. Coexistence of diabetes and psychiatric morbidities usually manifests as impaired quality of life and poor treatment adherence.

Objectives: The study aimed to estimate the prevalence of psychiatric morbidities among rural diabetic patients and to determine their association with different variables.

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Crude oil exploitation in the Niger Delta, particularly in Ogoniland, brought environmental devastation occasioned by petroleum pollution, as farmlands and water sources were destroyed. This study was designed to remediate crude oil contaminated water obtained from water sources in Ogoniland using two green algal species. Thirty water samples were collected from eight different water sources.

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  • Malaria control programs use various diagnostic methods like RDTs, microscopy, PCR, and BBA to assess malaria prevalence, but data comparing these methods, especially in high-burden areas like the DRC, is scarce.
  • The study analyzed samples from 1,431 participants in Kinshasa Province, revealing significant differences in Plasmodium falciparum prevalence rates across health areas, with BBA and PCR showing the highest sensitivity based on prevalence intensity.
  • RDTs demonstrated consistent specificity across all regions, but overall prevalence estimates varied significantly depending on the diagnostic method used, indicating the need for careful selection of diagnostic tools in malaria monitoring.
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Histidine-rich protein 2- (HRP2-) based rapid diagnostic tests (RDTs) are widely used to detect Plasmodium falciparum in sub-Saharan Africa. Reports of parasites with pfhrp2 and/or pfhrp3 (pfhrp2/3) gene deletions in Africa raise concerns about the long-term viability of HRP2-based RDTs. We evaluated changes in pfhrp2/3 deletion prevalence over time using a 2018-2021 longitudinal study of 1,635 enrolled individuals in Kinshasa Province, Democratic Republic of the Congo (DRC).

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Background: The reliance on blood for thin and thick blood smear microscopy-using a relatively invasive procedure has presented challenges to the use of reliable diagnostic tests in non-clinical settings at the point-of-need (PON). To improve the capacity of non-blood-based rapid diagnostic tests to confirm subclinical infections, and thereby identify and quantify the human reservoir at the PON, a cross-sectoral collaboration between university researchers and commercial partners produced an innovative, non-invasive saliva-based RDT capable of identifying novel, non-hrp2/3 parasite biomarkers. While this new saliva-based malaria asymptomatic and asexual rapid test (SMAART-1) shows increased detection sensitivity and precision potential by identifying a new P.

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Introduction: To complement the Swachhata Abhiyaan effort, the Ministry of Health and Family Welfare, initiated "KAYAKALP." Kayakalp is an initiative to improve the cleanliness, hygiene, and sanitation of public health facilities by recognizing and giving awards to those who exhibit a high level of cleanliness, hygiene, and infection control. Our study aimed to assess the level of cleanliness, hygiene, and infection control practices in the health care facility after undertaking by the department of Community Medicine of a medical college.

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This paper focuses on the development of maize plant datasets for the purposes of recognizing maize plants and weed species, as well as the precise automated application of herbicides to the weeds. The dataset includes 36,374 images captured with a high-resolution digital camera during the weed survey and 500 images annotated with the Labelmg suite. Images of the eighteen farmland locations in North Central Nigeria, containing the maize plants and their associated weeds were captured using a high-resolution camera in each location.

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There is growing evidence that parental trauma is associated with psychosocial disorders, externalizing and internalizing problems, and higher sensitivity to posttraumatic stress disorder (PTSD) in children. Recent research findings suggest multidimensional relational, psychological, and neurobiological interrelated pathways of intergenerational influence. Moreover, the intergenerational effects of parental trauma need to be understood within a broader systemic context, as a part of family adaptation.

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The recent advancements in Information and Communication Technology (ICT) as well as increasing demand for vehicular safety has led to significant progressions in Autonomous Vehicle (AV) technology. Perception and Localisation are major operations that determine the success of AV development and usage. Therefore, significant research has been carried out to provide AVs with the capabilities to not only sense and understand their surroundings efficiently, but also provide detailed information of the environment in the form of 3D maps.

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Subsidence, especially in populated areas, is becoming a threat to human life and property. Monitoring and analyzing the effects of subsidence over large areas using in situ measurements is difficult and depends on the size of the subsidence area and its location. It is also time-consuming and costly.

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Article Synopsis
  • Contagious ecthyma, or Orf, is a significant zoonotic disease impacting ruminants, posing economic challenges due to its effects on animal health and trade.
  • A study infected lamb testicle cells with a scab sample from an infected goat, confirming the Orf virus presence through PCR and sequencing its genome, which consists of 132,124 bp.
  • The analysis found that the Malaysian ORFV strain UPM/HSN-20 shares 97.3-99.0% similarity with other strains, particularly those from China, providing insights into genetic diversity and potential control strategies for the virus.
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The high stability and conductivity of 3,4-disubstituted polythiophenes such as poly(3,4-ethylenedioxythiophene) (PEDOT) make them attractive candidates for commercial applications. However, next-generation nanoelectronic devices require novel macromolecular strategies for the precise synthesis of advanced polymer structures as well as their arrangement. In this report, we present a synthetic route to make ladder-like polymer brushes with poly(3,4-propylenedioxythiophene) (PProDOT)-conjugated chains.

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In-situ bioremediation of mangrove soil contaminated with polyethylene terephthalate (PET) and polystyrene (PS) microplastics was investigated using indigenous microbial consortium with adequate capacity to degrade the plastics. Eight (8) bacteria were isolated from plastic/microplastic-inundated mangrove soil and screened for the ability to degrade PET and PS microplastics. Optical density at 600 nm and colony forming unit counts were measured to evaluate the growth response of the microbes in the presence of PS and PET microplastics at different times of exposure.

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We carried out a survey in the Czech Republic between January and February 2021 to evaluate the impact of COVID-19 on doctors working in the COVID-19 unit. A rise in 250,000 cases were seen in the Czech Republic during the time of the survey. The indirect impact of the disease on doctors working in COVID-19 units and strategies to control the situation in the Czech Republic were evaluated here.

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