Publications by authors named "Bakare-Odunola Taibat Moji"
Antimicrobial and antioxidant activity of catechin-3-o-rhamnoside isolated from the stem bark of Lannea kerstingii Engl. and K. Krause (Anacardiaceae).
Njinga Ngaitad Stanislaus Sule Mohammed Ibrahim Pateh Umar Usman Hassan Halimatu Sa'adiya Magaji Mohammed Garba Bakare-Odunola Taibat Moji
Pak J Pharm Sci
March 2021
Article Synopsis
- Epidemiological studies highlight the importance of fruits and vegetables for health; however, drug-resistant bacteria are becoming a significant concern, leading to increased mortality.
- A flavonoid called Catechin-3-o-rhamnoside was isolated from Lannea kerstingii using dry vacuum liquid chromatography and characterized with various NMR techniques.
- The compound demonstrated strong antimicrobial activity against several resistant bacteria and fungi, along with high antioxidant activity, suggesting its potential as a natural remedy for drug-resistant infections.
Allele and Genotype Frequencies of Cytochrome P450 2B6 516G>T Single Nucleotide Polymorphism in HIV-Negative and HIV-Infected Adult Nigerian Populations.
Abdullahi Saʼad Toyin Soyinka Julius Olugbenga Bolarinwa Rahman Ayodele Olarewaju Olusola Joseph Bakare-Odunola Taibat Moji
Am J Ther
February 2017
Polymorphisms in genes have been found in most enzymes involved in drug metabolism, especially in the cytochrome P450 (CYP) family with considerable ethnic differences in their frequencies. Single nucleotide polymorphisms (SNPs) are the major source of these genetic variations. CYP2B6 516G>T SNP found in both CYP2B6*6 and CYP2B6*9 alleles significantly reduces CYP2B6 protein expression and enzyme activity with important implications on the pharmacokinetics and pharmacodynamic outcomes of some clinically relevant drug substrates.
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