Publications by authors named "Bain A"

How does the fig tree Ficus benguetensis protect its investment in the production of figs and pollinating fig wasps against parasitism from non-pollinating fig wasps? This study documents a previously overlooked defense mechanism: fig abscission-the natural shedding of the fig fruit as a defense mechanism. Our bagging experiments showed that both the absence of pollination and high parasitism levels lead to the abortion of F. benguetensis figs, with positive correlations between parasitism levels, increased abscission rates, and decreased pollinator production.

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  • ECMO (extracorporeal membranous oxygenation) is explored as a treatment option for patients with severe ARDS, particularly in burn cases where previous experience is limited.
  • A case study details a 40-year-old woman with significant burns and severe inhalation injury who was placed on veno-venous ECMO for over 21 days while undergoing multiple surgical procedures and receiving extensive blood product transfusions.
  • The report emphasizes the challenges and complexities of managing ECMO support during burn excision surgery, highlighting the need for further research on patient management strategies and the timing of interventions in such cases.
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Surfactants are important components of atmospheric aerosols, potentially impacting their hygroscopic growth and eventual activation into cloud droplets. By adsorbing at the air-water interface, surfactants lower the surface tension of aqueous systems. However, in microscopic aerosol droplets, the bulk surfactant concentration can become depleted because of the droplets' high surface-area-to-volume ratio, reducing the bulk surfactant concentration at equilibrium and increasing droplet surface tension.

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  • - An estimated 65 million people globally experience post-acute sequelae of COVID-19 (PASC), with many suffering from specific cardiovascular symptoms (PASC-CVS) like chest pain and heart palpitations.
  • - The study focuses on chronic inflammation in PASC-CVS patients, particularly those with symptoms lasting over a year, and shows a distinct blood signature indicating inflammation linked to their condition.
  • - Findings reveal trace levels of pro-inflammatory cytokines and elevated complement and coagulation proteins in the blood of PASC-CVS patients, suggesting that chronic inflammation significantly impacts heart function in these individuals.
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Background: Goal-concordant care (GCC) is recognized as the highest quality of care and most important outcome measure for serious illness research, yet there is no agreed-upon or validated method to measure it.

Objective: Assess feasibility of measuring GCC using clinical documentation in the electronic health record (EHR).

Design: Retrospective chart review study.

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Microneurographic recordings of the human cervical vagus nerve have revealed the presence of multi-unit neural activity with measurable cardiac rhythmicity. This suggests that the physiology of vagal neurones with cardiovascular regulatory function can be studied using this method. Here, the activity of cardiac rhythmic single units was discriminated from human cervical vagus nerve recordings using template-based waveform matching.

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  • This study explores the significant risk of recurrence in early-stage lung adenocarcinoma after surgical removal, noting that current methods lack biomarkers for prediction.
  • Researchers analyzed 91 patients' tumor and nearby unaffected lung tissue using specialized gene sequencing techniques to identify potential microbial and host genomic factors associated with recurrence.
  • Results revealed specific bacterial enrichments linked to recurrence in both tumor (e.g., Dialister) and unaffected lung samples (e.g., Sphingomonas), with a combined model showing strong predictive performance for recurrence using unaffected lung samples (AUC = 0.83).
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Introduction: We sought to identify predictors of failed retrograde ureteric stent (FRS) placement in the setting of obstructing ureteric calculi. In addition to patient- and stone-specific characteristics, we also considered computed tomography (CT) measures of ureteric wall thickness (UWT), as it has shown clinical potential in predicting outcomes of shockwave lithotripsy, ureteroscopy, and spontaneous stone passage.

Methods: We performed a retrospective, case-control study comparing patients who had successful retrograde stent (SRS) insertions with those who failed stent placement and ultimately required nephrostomy tube (NT) insertion (2013-2019).

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Digital therapeutics (DTx) is a recently conceived idea in health care that aims to cure ailments and modify patient behavior by employing a range of digital technologies. Notably, when traditional medication is not entirely efficacious, DTx offers an innovative avenue for treatments linked to dysfunctional behaviors and lifestyle management. DTx involves extremely adaptable therapeutic devices that empower greater patient engagement in treating illness, using algorithms to collect, transfer and analyze the patient's data.

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Aim: How the cerebral metabolic rates of oxygen and glucose utilization (CMRO and CMR, respectively) are affected by alterations in arterial PCO (PaCO) is equivocal and therefore was the primary question of this study.

Methods: This retrospective analysis involved pooled data from four separate studies, involving 41 healthy adults (35 males/6 females). Participants completed stepwise steady-state alterations in PaCO ranging between 30 and 60 mmHg.

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Aerosol droplets are unique microcompartments with relevance to areas as diverse as materials and chemical synthesis, atmospheric chemistry, and cloud formation. Observations of highly accelerated and unusual chemistry taking place in such droplets have challenged our understanding of chemical kinetics in these microscopic systems. Due to their large surface-area-to-volume ratios, interfacial processes can play a dominant role in governing chemical reactivity and other processes in droplets.

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Aim: Plants distributed between southern Taiwan and the north of the Philippines are spread among numerous small islands in an area crossed by the powerful Kuroshio current. Oceanic currents can be effective seed-dispersal agents for coastal plant species. Moreover, the Luzon Strait is an area prone to tropical cyclones.

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Despite elite human free divers achieving incredible feats in competitive free diving, there has yet to be a study that compares consummate divers, (i.e. northern elephant seals) to highly conditioned free divers (i.

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  • The study evaluates whether healthcare providers can effectively classify patients' goals of care from electronic health records, focusing on patients with high mortality risk.
  • The analysis revealed that the most common initial goal was "life extension," but many patients shifted toward "comfort-focused" goals over time.
  • Barriers to clear goal classification included mixed goals, uncertainty among patients and families, and insufficient documentation.
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  • The study investigates how extreme changes in oxygen and carbon dioxide levels during apnoea affect the brain's energy function and oxidative stress.
  • Ten highly trained apnoeists were tested under two conditions: one with low oxygen and high carbon dioxide, and another with high oxygen and high carbon dioxide.
  • Results showed that prolonged apnoea increased blood flow to the brain, but this was not enough to maintain normal rates of oxygen and glucose consumption, indicating increased oxidative stress.
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Recent studies have challenged assumptions about the classic fig-fig wasp pollination mutualism model, suggesting that further investigation into the receptive phase of fig development is needed. This study assessed the pollination mechanisms of Ficus septica in southern Taiwan and identified two species of wasps as the primary pollinators. Machine learning was used to identify and rank the factors that explain the relative abundance of these wasps.

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The surface composition of aerosol droplets is central to predicting cloud droplet number concentrations, understanding atmospheric pollutant transformation, and interpreting observations of accelerated droplet chemistry. Due to the large surface-area-to-volume ratios of aerosol droplets, adsorption of surfactant at the air-liquid interface can deplete the droplet's bulk concentration, leading to droplet surface compositions that do not match those of the solutions that produced them. Through direct measurements of individual surfactant-containing, micrometer-sized droplet surface tensions, and fully independent predictive thermodynamic modeling of droplet surface tension, we demonstrate that, for strong surfactants, the droplet's surface-area-to-volume ratio becomes the key factor in determining droplet surface tension rather than differences in surfactant properties.

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Organosulfates comprise up to 30% of the organic fraction of aerosol. Organosulfate aerosol physical properties, such as water activity, density, refractive index, and surface tension, are key to predicting their impact on global climate. However, current understanding of these properties is limited.

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Passive hyperthermia causes cerebral hypoperfusion primarily from heat-induced respiratory alkalosis. However, despite the cerebral hypoperfusion, it is possible that the mild alkalosis might help to attenuate cerebral inflammation. In this study, the cerebral exchange of extracellular vesicles (microvesicles), which are known to elicit pro-inflammatory responses when released in conditions of stress, were examined in hyperthermia with and without respiratory alkalosis.

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Background: The prevalence of chronic kidney disease (CKD) is rising in Malaysia. Early detection is necessary to prevent disease progression, especially in terms of cardiovascular (CV) risk, the main cause of death in end-stage renal disease (ESRD). Retinal changes have proven to be a good predictor of CKD whereas cardiac biomarkers are useful in cardiovascular risk stratification.

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The development of a Marjolin ulcer at the site of a split-thickness skin graft donor site is exceptionally rare. Here we describe the rapid development of squamous cell carcinoma at a split-thickness skin graft donor site in the setting of severe burn. We present a case of a 52-year-old male with no past medical history who presented with a 24% total body surface area burn caused by a flash flame.

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