Publications by authors named "Baimba Idriss"
Precis: Using optical coherence tomography (OCT) measurements as a reference standard for vertical cup-to-disc ratio (vCDR), a smartphone-based ophthalmic camera has a sensitivity of 67.7% and specificity of 96.7% to detect a vCDR>0.
View Article and Find Full Text PDFBackground: TKM-130803, a small interfering RNA lipid nanoparticle product, has been developed for the treatment of Ebola virus disease (EVD), but its efficacy and safety in humans has not been evaluated.
Methods And Findings: In this single-arm phase 2 trial, adults with laboratory-confirmed EVD received 0.3 mg/kg of TKM-130803 by intravenous infusion once daily for up to 7 d.
Thousands of persons have survived Ebola virus disease. Almost all survivors describe symptoms that persist or develop after hospital discharge. A cross-sectional survey of the symptoms of all survivors from the Ebola treatment unit (ETU) at 34th Regimental Military Hospital, Freetown, Sierra Leone (MH34), was conducted after discharge at their initial follow-up appointment within 3 weeks after their second negative PCR result.
View Article and Find Full Text PDFArticle Synopsis
- Ebola virus RNA was detected in the semen of 27% of male survivors of Ebola virus disease in Sierra Leone, with varying detection rates depending on the time since discharge from treatment.
- The study surveyed 220 male survivors with semen samples tested using RT-PCR methods, revealing a higher prevalence of viral RNA shortly after discharge and a significant decline over time.
- The findings highlight the need for further research into the potential risks of sexual transmission of Ebola, as the study did not directly assess this aspect.