Publications by authors named "Bailong Hou"

Article Synopsis
  • This study examined carbapenem-resistant Klebsiella pneumoniae (CRKP) strains in a Chinese hospital, focusing on their resistance to multiple antibiotics, including aminoglycosides and tigecycline.
  • Samples from ten CRKP strains were collected, and various tests including antimicrobial susceptibility testing and whole-genome sequencing were conducted to assess resistance mechanisms and gene transfer.
  • The results revealed that these strains had high antibiotic resistance, identified critical resistance genes, and showed potential for clonal and horizontal transfer, marking them as significant public health threats.
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Embedded silver nanoparticles (Ag NPs) within nanofibers represent a highly promising alternative to common antimicrobial materials, due to the combined effective biocidal properties of Ag NPs with the biocompatibility and environmental friendliness of biobased polymers. In this study, we presented a novel one-step route to fabricate biobased polyamide 56 (PA56) nanofibers embedded with uniform Ag NPs. The process involved mixing reactive silver ammonia with PA56 solutions and then using formic acid as a reducing agent.

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Background: To investigate the existence and degree of correlation between benign ovarian tumors and physiological indicators such as reproductive hormones and tumor markers.

Methods: A total of 150 patients with benign ovarian tumors admitted to Jiaxing First Hospital between January 1, 2019, and May 30, 2021, were enrolled as research subjects, while 104 healthy women were enrolled in the control group. Comparative analysis of the correlation between the reproductive hormones LH, FSH, T, E2, and the tumor indicators AMH, AFP, CEA, CA125, and CA199 between the groups was performed.

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Cervical cancer, the second most common cause of cancer death in women worldwide, is significantly associated with infection of high-risk human papillomaviruses (HPVs), especially the most common genotype, HPV 16. To date, there is no established noninvasive therapy to treat cervical cancer. Here, we report a novel affitoxin that targets HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer.

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The electrochemical behavior of trivalent chromium reduction from 1-butyl-3-methylimidazolium-bromide ([BMIM]Br) ionic liquid is studied. The result of cyclic voltammetry shows that the Cr(III) reduction is irreversible and occurs in two steps, Cr(III)to Cr(II), and Cr(II) to Cr(0), respectively. In the electrochemical impedance spectroscopy measurements, the preferable equivalent circuit is made to fit the experimental data.

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We evaluated the immunogenicity and efficacy of a candidate vaccine comprising the major outer membrane protein (MOMP) multi-epitope of Chlamydia trachomatis. A short gene of multi-epitope derived from MOMP containing multiple T- and B-cell epitopes was artificially synthesized. The recombinant plasmid pET32a(+) containing codon optimized MOMP multi-epitope gene was constructed.

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The nano Fe-Ni-Cr/SiC composite coatings were prepared using pulse electrodeposition method from trivalent chromium baths containing compound carboxylate-urea system and nano SiC in ultrasonic field. The effects of the carboxylate-urea system on the nano Fe-Ni-Cr/SiC composite coatings have been investigated. These results indicated that the SiC and Cr contents and the thickness of the Fe-Ni-Cr/SiC composite coatings could be obviously improved by the compound carboxylate-urea system.

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The effects of compound carboxylate-urea system on the nano Ni-Cr/SiC composite coatings from trivalent chromium baths have been investigated in ultrasonic field. These results indicated that the SiC and Cr contents and the thickness of the Ni-Cr/SiC composite coatings could be obviously improved by the compound carboxylate-urea system. The steady-state polarization curves showed that the hydrogen evolution reaction (HER) could be significantly inhibited by the compound carboxylate-urea system, which was benefit to increase the SiC and Cr contents and the thickness of the composite coatings.

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