Coupling isotopic signatures and partial extraction method to examine lead pollution in mangrove sediments.

Elevated lead (Pb) has been widely observed in mangrove sediments due to human activities, yet understanding the sources of Pb in these sediments and the factors influencing Pb accumulation is challenging. Here, we combined Pb isotopes with partial extraction methods to study Pb contamination levels in mangrove sediments from the eastern and western parts of the Maowei Sea, China. Our results showed that the Pb in the leachate and residual fraction was mainly from anthropogenic and natural sources, respectively.

The non-coevolution of DIC and alkalinity and the CO degassing in a karst river affected by acid mine drainage in Southwest China.

Dissolved inorganic carbon (DIC) in mine water generated during coal mining is a large and potential source of atmospheric CO, however its geochemical behaviors under the influence of AMD in relation to CO degassing and carbonate buffering are not well known. In this study, water temperature, pH, DO, alkalinity, Ca concentration, and the carbon isotope of DIC were measured monthly from November 2020 to November 2021 and carbonate chemistry and CO emission flux were calculated to reveal the processes of DIC evolution and CO degassing from the Chetian River draining a karst region, which is materially affected by the input of large quantities of AMD. The results showed that carbonate erosion, the mineralization of terrestrial organic matter, and domestic sewage input are all identified to contribute DIC to different degrees to the river.

Polychlorinated biphenyl quinone induces hepatocytes iron overload through up-regulating hepcidin expression.

Polychlorinated biphenyls (PCBs) are infamous industry by-products or additives, and increasing evidences demonstrated that their exposure is associate with adverse effects on human health. Liver, as the dominate site for xenobiotic metabolism, is apt to be the primary target of PCBs insult. Although PCBs' hepatic toxic effects have been extensively studied, however, the biotransformation of PCBs in liver and the toxicities of associated PCB metabolites are neglected at some extent.

Polychlorinated biphenyl quinone promotes macrophage polarization to CD163 cells through Nrf2 signaling pathway.

Polychlorinated biphenyls (PCBs) are notorious environmental pollutants. For their hydrophobic and lipophilic capability, they are wildly spread to environment to threat human health thus attracts more attention. In this study, we observed increasing numbers of CD163 positive (CD163) macrophages in aortic valve of ApoE mice after 2,3,5-trichloro-6-phenyl-[1,4]-benzoquinone (PCB29-pQ) treatment, the metabolite of polychlorinated biphenyl.