Collagen and α-Tubulin of Mouse Tympanic Membrane Fibroblasts Treated with Quinolones and Aminoglycosides.

Objective To assess collagen and α-tubulin levels of mouse tympanic membrane fibroblasts treated with quinolone and aminoglycoside antibiotics at concentrations found in eardrops. Study Design Prospective controlled cell culture study. Setting Academic tertiary medical center.

Ciprofloxacin Decreases Collagen in Mouse Tympanic Membrane Fibroblasts.

Objectives: To determine how collagen production by tympanic membrane fibroblasts is affected by ciprofloxacin at levels found in eardrops.

Study Design: Prospective, controlled, and blinded cell culture study.

Setting: Academic tertiary medical center.