Complete genome sequence of sp. SCR221107, encoding biosynthesis of vitamin B isolated from the rumen fluid of Holstein dairy cows.

sp. SCR221107 was isolated from the rumen fluid of healthy male Holstein dairy cows from a research farm at Suncheon, Jeollanam-do, Korea. sp.

Prevention of occlusal caries using Vanish XT: an 18-month follow-up randomized clinical trial.

Aim: To evaluate the effectiveness of a light curable resin-modified glass ionomer varnish (Vanish XT) in the prevention of occlusal caries compared to topical fluoride varnish in newly erupted first permanent molars over 18 months.

Methods: A randomized controlled clinical trial was conducted using a split-mouth design. A total of 53 participants aged 6-9 years with 97 pairs of caries-free newly erupted first permanent molars were enrolled in the study.

Protective Effects of Sesame Glycoproteins on Ultraviolet-Induced Skin Aging: In Vitro and In Vivo Studies.

Background/objectives: Ultraviolet (UV) radiation is a primary factor in skin photoaging, leading to wrinkles, reduced elasticity, and pigmentation changes due to damage to cellular DNA, proteins, and lipids. Glycoproteins from sesame cake (SPE) have potential protective effects against UV-induced skin aging. This study investigated the anti-photoaging effects of SPE on UV-induced damage in human keratinocyte HaCaT cells and SKH-1 hairless mice.

Association between striatal amyloid deposition and motor prognosis in Parkinson's disease.

Background And Purpose: The co-occurrence of amyloid-β pathology in Parkinson's disease (PD) is common; however, the role of amyloid-β deposition in motor prognosis remains elusive. This study aimed to investigate the association between striatal amyloid deposition, motor complications and motor prognosis in patients with PD.

Methods: Ninety-six patients with PD who underwent F florbetaben (FBB) positron emission tomography were retrospectively assessed.

Ocular Vestibular-Evoked Myogenic Potential Assists in the Differentiation of Multiple System Atrophy From Parkinson's Disease.

Objective: Vestibular-evoked myogenic potentials (VEMPs) can help in assessing otolithic neural pathway in the brainstem, which may also contribute to the cardiovascular autonomic function. Parkinson's disease (PD) is associated with altered VEMP responses; however, the associations between VEMP abnormalities and multiple system atrophy (MSA) remain unknown. Therefore, we compared the extent of otolith dysfunction using ocular (oVEMP) and cervical VEMPs between patients with MSA and PD.

A Full Mouth Rehabilitation of an Asthma-Associated Patient With Tooth Surface Loss: A Case Report.

Tooth surface loss (TSL) is multifactorial and, when severe, it can severely impact the quality of life. Although carbonated soft drinks, with their high sugar and acid content, are a common cause of TSL, the effects do not usually mandate full-mouth rehabilitation. Nevertheless, when combined with other factors such as parafunctional habits or other drivers of high consumption, TSL can be severe.

Neck rigidity: a pitfall for video head-impulse tests in Parkinson's disease.

Video head impulse tests (video-HITs) are commonly used for vestibular evaluation; however, the results can be contaminated by various artifacts, including technical errors, recording problems, and participant factors. Although video-HITs can be used in patients with Parkinson's disease (PD), the effect of neck rigidity has not been systematically investigated. This study aimed to investigate the effect of neck rigidity on video-HIT results in patients with PD.

Parkinson's disease with hyposmia and dysautonomia: does it represent a distinct subtype?

Background And Purpose: Olfactory dysfunction or dysautonomia is one of the earliest prodromal nonmotor symptoms of Parkinson's disease (PD). We aimed to investigate whether PD patients with dysautonomia and hyposmia at the de novo stage present different prognoses regarding PD dementia (PDD) conversion, motor complication development, and change in levodopa-equivalent doses (LED).

Methods: In this retrograde cohort study, we included 105 patients with newly diagnosed PD patients who underwent cross-cultural smell identification test (CC-SIT), autonomic function tests (AFT), and dopamine transporter (DAT) scan at the de novo stage.

Development and Validation of a Screening Questionnaire for Dementia With Lewy Bodies (DLB): the DLB Screening Questionnaire (DLBSQ).

Background And Purpose: Although dementia with Lewy bodies (DLB) is the second most common cause of neurodegenerative dementia, its clinical prevalence is low. We developed a short and easy-to-complete DLB screening questionnaire (DLBSQ) to raise diagnostic sensitivity in routine clinical settings.

Methods: A total of 501 participants were retrospectively enrolled, including 71 controls, 184 patients without DLB, and 246 patients with probable DLB.

Children's communication repair strategies: Online versus face-to-face interaction.

Introduction: One's ability to repair communication breakdown is an important pragmatic language skill. The present study examined children's communication repair strategies between online and face-to-face interactions using a reading comprehension task designed to probe for persistent clarification requests.

Methods: 4-6-year-old typically developing children (Age: M = 5.

Functional Brain Networks of Minor and Well-Structured Major Hallucinations in Parkinson's Disease.

Background: Minor hallucinations (mHs) and well-structured major hallucinations (MHs) are common symptoms of Parkinson's disease (PD) psychosis.

Objectives: To investigate the resting-state networks (RSNs) in patients with PD without hallucinations (PD-nH), with mH (PD-mH), and with MH (PD-MH).

Methods: A total of 73 patients with PD were enrolled (27 PD-nH, 23 PD-mH, and 23 PD-MH).

Digital evaluation of occlusal reduction of metal crown preparations in students in the COVID-19 era: A cross-sectional study.

Introduction: Occlusion of extra-coronal restorations depends on the reduction achieved during crown preparation. Ensuring adequate reduction is therefore essential for the success of the final restoration. The objective of this study was to digitally quantify the occlusal reduction performed by preclinical undergraduate dental students and to compare their performance across the year and using a hybrid teaching approach developed because of the COVID-19 pandemic.

Quality of post and core placement by final year undergraduate dental students.

The success of endodontic restoration of badly compromised teeth depends on the quality of post and core placement and the extra-coronal restoration. Ensuring that students place posts to acceptable quality standards is therefore essential. The aim of this study was to radiographically evaluate post placement by final year undergraduate dental students and to identify any predictors of performance.

Distinct amyloid-dependent patterns of nigra dopamine depletion in Lewy body diseases.

Introduction: Concomitant amyloid pathology is not uncommon and contributes to the clinical characteristics of Lewy body disease (LBD). We investigated the effect of amyloid on striatalF-FP-CIT uptake patterns in LBD, including Parkinson's disease (PD) and dementia with Lewy bodies.

Methods: We enrolled 125 patients with LBD who underwentF-florbetaben positron emission tomography (PET) andF-FP-CIT PET.

Association of Neuropsychiatric Symptom Profiles With Cognitive Decline in Patients With Parkinson Disease and Mild Cognitive Impairment.

Background And Objectives: Neuropsychiatric symptoms (NPS) are closely associated with cognitive decline in patients with Parkinson disease (PD). We investigated which profiles of NPS are associated with the risk of dementia in PD with mild cognitive impairment (PD-MCI).

Methods: We retrospectively assessed 338 patients with PD-MCI from a single tertiary hospital, who underwent neuropsychological tests and a neuropsychiatric inventory (NPI) questionnaire.

Neuropsychological Comparison of Patients With Alzheimer's Disease and Dementia With Lewy Bodies.

Background And Purpose: This study aimed to determine the neuropsychological differences between patients with early-stage Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) with a Clinical Dementia Rating (CDR) score of ≤1.

Methods: We examined 168 patients with AD (126 with CDR score=0.5, 42 with CDR score=1) and 169 patients with DLB (104 with CDR score=0.

Integration of blue light with near-infrared irradiation accelerates the osteogenic differentiation of human dental pulp stem cells.

Blue light is used less in photobiomodulation than red or near-infrared light because of concerns about its high energy. However, some reports have suggested that blue light releases NO from nitrosated proteins, affects cell signal regulation, and promotes stem cell differentiation. Because blue and red lights could have different mechanisms of action, their combination is expected to have new consequences.

Substantia nigral dopamine transporter uptake in dementia with Lewy bodies.

Nigrostriatal dopaminergic degeneration is a pathological hallmark of dementia with Lewy bodies (DLB). To identify the subregional dopamine transporter (DAT) uptake patterns that improve the diagnostic accuracy of DLB, we analyzed N-(3-[F] fluoropropyl)-2β-carbomethoxy-3β-(4-iodophenyl)-nortropane (FP-CIT) PET in 51 patients with DLB, in 36 patients with mild cognitive impairment with Lewy body (MCI-LB), and in 40 healthy controls (HCs). In addition to a high affinity for DAT, FP-CIT show a modest affinity to serotonin or norepinephrine transporters.

Selective Denervation for the Thumb Carpometacarpal Joint: Clinical Outcome and Comparison Based on Eaton Stage.

Purpose: Various operative treatment options for advanced thumb carpometacarpal (CMC) joint arthritis have been presented without a definite surgical guideline. Selective denervation is a less invasive method for thumb CMC arthritis. However, it is unclear whether the clinical outcome varies with the stage of thumb CMC arthritis.

Histological Response to 5 kHz Irreversible Electroporation in a Porcine Liver Model.

Unlike necrosis by thermal ablation, irreversible electroporation (IRE) is known to induce apoptosis by disrupting plasma membrane integrity with electric pulses while preserving the structure of blood vessels and bile ducts in liver tissue without a heat sink effect. This study aimed to investigate thermal damage and histopathological effects in the porcine liver by high-frequency electric pulses (5 kHz) which is much higher than the widely used 1 Hz. The electric field and thermal distributions of 5 kHz electric pulses were compared with those of 1 Hz in numerical simulations.