Currently, aeroplane images captured by camera sensors are characterized by their small size and intricate backgrounds, posing a challenge for existing deep learning algorithms in effectively detecting small targets. This paper incorporates the RFBNet (a coordinate attention mechanism) and the SIOU loss function into the YOLOv5 algorithm to address this issue. The result is developing the model for aeroplane and undercarriage detection.
View Article and Find Full Text PDFComput Methods Programs Biomed
September 2022
Background And Objective: Upper-limb amputation can significantly affect a person's capabilities with a dramatic impact on their quality of life. As a biological signal, surface electromyogram (sEMG) provides a non-invasive means to measure underlying muscle activation patterns, corresponding to specific hand gestures. This project aims to develop a real-time deep learning based recognition model to automatically and reliably recognise these complex signals of a wide range of daily hand gestures from amputees and non-amputees.
View Article and Find Full Text PDFSoluble tumor necrosis factor-α (sTNF-α) plays an important role in colitis-associated cancer (CAC); however, little is known about transmembrane TNF-α (tmTNF-α). Here, we observed an increase in sTNF-α mainly in colitis tissues from an azoxymethane/dextran sodium sulfate (DSS)-induced CAC mouse model whereas tmTNF-α levels were chiefly increased on epithelial cells at the tumor stage. The ratio of intracolonic tmTNF-α/sTNF-α was negatively correlated with the levels of pro-inflammatory mediators (IL-1β, IL-6, and NO) and M1 macrophages but positively correlated with the infiltration of myeloid-derived suppressor cells, regulatory T cells, and the level of the anti-inflammatory cytokine IL-10, suggesting an anti-inflammatory effect of tmTNF-α.
View Article and Find Full Text PDFBackground: Hemophagocytic lymphohistiocytosis (HLH) associated with B-cell lymphoma is a highly aggressive disease with unclear clinical features and has no standard treatment.
Patients And Methods: We analyzed the clinical characteristics of 31 patients from two individual centers.
Results: The median overall survival was only 1.
IEEE Trans Vis Comput Graph
June 2020
Material appearance of rendered objects depends on the underlying BRDF implementation used by rendering software packages. A lack of standards to exchange material parameters and data (between tools) means that artists in digital 3D prototyping and design, manually match the appearance of materials to a reference image. Since their effect on rendered output is often non-uniform and counter intuitive, selecting appropriate parameterisations for BRDF models is far from straightforward.
View Article and Find Full Text PDFMost of the current blind stereoscopic image quality assessment (SIQA) algorithms cannot show reliable accuracy. One reason is that they do not have the deep architectures and the other reason is that they are designed on the relatively weak biological basis, compared with findings on human visual system (HVS). In this paper, we propose a Deep Edge and COlor Signal INtegrity Evaluator (DECOSINE) based on the whole visual perception route from eyes to the frontal lobe, and especially focus on edge and color signal processing in retinal ganglion cells (RGC) and lateral geniculate nucleus (LGN).
View Article and Find Full Text PDFIEEE Trans Cybern
January 2020
An image is compressed or stretched during the multidevice displaying, which will have a very big impact on perception quality. In order to solve this problem, a variety of image retargeting methods have been proposed for the retargeting process. However, how to evaluate the results of different image retargeting is a very critical issue.
View Article and Find Full Text PDFThis paper proposes a novel Adaptive Region-based Edge Smoothing Model (ARESM) for automatic boundary detection of optic disc and cup to aid automatic glaucoma diagnosis. The novelty of our approach consists of two aspects: 1) automatic detection of initial optimum object boundary based on a Region Classification Model (RCM) in a pixel-level multidimensional feature space; 2) an Adaptive Edge Smoothing Update model (AESU) of contour points (e.g.
View Article and Find Full Text PDFBackground: This study compared the accuracy of measuring shoulder range of movement (ROM) with a simple laptop-sensor combination vs. trained observers (shoulder physiotherapists and shoulder surgeons) using motion capture (MoCap) laboratory equipment as the gold standard.
Methods: The Microsoft Kinect sensor (Microsoft Corp.
Autism spectrum condition (ASC) is primarily diagnosed by behavioural symptoms including social, sensory and motor aspects. Although stereotyped, repetitive motor movements are considered during diagnosis, quantitative measures that identify kinematic characteristics in the movement patterns of autistic individuals are poorly studied, preventing advances in understanding the aetiology of motor impairment, or whether a wider range of motor characteristics could be used for diagnosis. The aim of this study was to investigate whether data-driven machine learning based methods could be used to address some fundamental problems with regard to identifying discriminative test conditions and kinematic parameters to classify between ASC and neurotypical controls.
View Article and Find Full Text PDFMyeloid-derived suppressor cells (MDSCs) accumulated in tumor sites promote immune evasion. We found that TNFR deficiency-induced rejection of transplanted tumor was accompanied with markedly decreased accumulation of MDSCs. However, the mechanism(s) behind this phenomenon is not completely understood.
View Article and Find Full Text PDFBlind quality assessment of 3D images is used to confront more real challenges than 2D images. In this Letter, we develop a no-reference stereoscopic image quality assessment (SIQA) model based on the proposed left and right (LR)-similarity map and structural degradation. In the proposed method, local binary pattern features are extracted from the cyclopean image that are effective for describing the distortion of 3D images.
View Article and Find Full Text PDFTo design an effective antibody therapy to improve clinical outcomes in leukemia, the identification of novel cell surface antigens is needed. Herein, we demonstrate a role for transmembrane tumor necrosis factor-α (tmTNF-α) in leukemia. To characterize tmTNF-α expression in acute leukemia (AL), normal hematopoietic cells, and nonhematopoietic tissues, we used a monoclonal antibody, termed C1, which specifically recognizes the tmTNF-α domain.
View Article and Find Full Text PDFScanning laser ophthalmoscopes (SLOs) can be used for early detection of retinal diseases. With the advent of latest screening technology, the advantage of using SLO is its wide field of view, which can image a large part of the retina for better diagnosis of the retinal diseases. On the other hand, during the imaging process, artefacts such as eyelashes and eyelids are also imaged along with the retinal area.
View Article and Find Full Text PDFIt has been reported that TNFR2 is involved in regulatory T cell induction and myeloid-derived suppressor cell (MDSC) accumulation, two kinds of immunosuppressive cells contributing to tumor immune evasion. Because transmembrane TNF-α (tmTNF-α) is the primary ligand for TNFR2, we hypothesized that tmTNF-α is mainly responsible for the activation of MDSCs. Indeed, we found that tmTNF-α, rather than secretory TNF-α (sTNF-α), activated MDSCs with enhanced suppressive activities, including upregulating arginase-1 and inducible NO synthase transcription, promoting secretion of NO, reactive oxygen species, IL-10, and TGF-β, and enhancing inhibition of lymphocyte proliferation.
View Article and Find Full Text PDFGlaucoma is a group of eye diseases that have common traits such as, high eye pressure, damage to the Optic Nerve Head and gradual vision loss. It affects peripheral vision and eventually leads to blindness if left untreated. The current common methods of pre-diagnosis of Glaucoma include measurement of Intra-Ocular Pressure (IOP) using Tonometer, Pachymetry, Gonioscopy; which are performed manually by the clinicians.
View Article and Find Full Text PDFIEEE Trans Biomed Eng
July 2013
We address the problem of tracking in vivo muscle fascicle shape and length changes using ultrasound video sequences. Quantifying fascicle behavior is required to improve understanding of the functional significance of a muscle's geometric properties. Ultrasound imaging provides a noninvasive means of capturing information on fascicle behavior during dynamic movements; to date however, computational approaches to assess such images are limited.
View Article and Find Full Text PDFTumor necrosis factor alpha (TNF-α) has been implicated in the pathogenesis of Crohn's disease. TNF antagonists are effectively used to treat these patients, although the efficiency of different antagonists varies. In the present study we combined TNF-α binding cyclic peptide (TBCP) and TNFR1 binding cyclic peptide (TRBCP) to treat TNBS-induced colitis in rats for one week.
View Article and Find Full Text PDFBeijing Da Xue Xue Bao Yi Xue Ban
February 2007
Objective: To investigate the effects of lycopene on T lymphocyte subpopulations and pulmonary alveolar macrophagic (PAM) functions in rats with acute lung injury (ALI).
Methods: Rats were randomly divided into the following groups. (1) Control group, (2) ALI model group, (3) Low dose group,(4) Mid dose group and (5) High dose group.
IEEE Trans Syst Man Cybern B Cybern
June 2004
We propose a general algorithm for identifying an arbitrary pose of an articulated subject with sparse point features. The algorithm aims to identify a one-to-one correspondence between a model point-set and an observed point-set taken from freeform motion of the articulated subject. We avoid common assumptions such as pose similarity or small motions with respect to the model, and assume no prior knowledge from which to infer an initial or partial correspondence between the two point-sets.
View Article and Find Full Text PDFSheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
January 1997
Lp(a) receptor and LDL receptor on rhesus monkey liver cellular membrane were studied by Western blotting, to investigate whether Lp(a) and LDL metabolize through the same route. The experiment demonstrated Lp(a) receptor ( 300kD) and LDL receptor ( 185kD) to be different kinds of receptors. The result reveals that Lp(a) has its own metabolic pathway.
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