Publications by authors named "Baihan Zeng"
Article Synopsis
- Recent research indicates that a high salt diet (HSD) is associated with increased inflammation and decreased extracellular matrix (ECM) in the skin, leading to accelerated skin aging in mice.
- In a study with Wistar rats, those on an HSD for 8 weeks showed thickened epidermis and changes in molecular markers linked to aging, including elevated levels of cell cycle inhibitors and oxidative stress.
- By the end of the study, significant increases in inflammatory molecules were observed in the HSD group, suggesting that high salt intake contributes to skin aging through oxidative stress and inflammatory responses.
As an unhealthy dietary habit, a high-salt diet can affect the body's endocrine system and metabolic processes. As one of the most important metabolites, bile acids can prevent atherosclerosis and reduce the risk of developing cardiovascular diseases. Therefore, in the present study, we aimed to reveal the bile acid metabolism changes in salt-sensitive hypertension-induced vascular endothelial injury.
View Article and Find Full Text PDFHyperlipidemia has become a leading risk factor for cardiovascular diseases and liver injury worldwide. Fructus Phyllanthi (FP) is an effective drug against hyperlipidemia in Traditional Chinese Medicine (TCM) and Indian Medicine theories, however the potential mechanism requires further exploration. The present research aims to reveal the mechanism of FP against hyperlipidemia based on an integrated strategy combining network pharmacology prediction with metabolomics validation.
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