Publications by authors named "Bai-Chen Mu"
Background: Heart failure (HF), especially HF with reduced ejection fraction (HFrEF), presents complex challenges, particularly in the aging population where it often coexists with type 2 diabetes mellitus (T2DM).
Aim: To analyze the effect of dapagliflozin treatment on cardiac, renal function, and safety in patients with HFrEF combined with T2DM.
Methods: Patients with T2DM complicated with HFrEF who underwent treatment in our hospital from February 2018 to March 2023 were retrospectively analyzed as the subjects of this study.
Effects of hydroxysafflor yellow A on rats with collagen-induced arthritis.
Biochem Biophys Res Commun
September 2021
Article Synopsis
- Hydroxysafflor yellow A (HSYA), derived from safflower, shows potential in treating rheumatoid arthritis (RA) by reducing inflammation and joint damage.
- In a study on rats with collagen-induced arthritis, HSYA treatment resulted in lower paw swelling, improved pathological conditions, and decreased inflammatory substances in the blood.
- The highest dose of HSYA (20 mg/kg) demonstrated the most significant therapeutic effects by inhibiting the ERK signalling pathway, suggesting a mechanism for its anti-inflammatory action.