Right ventricular geometry and mechanics in patients with obstructive sleep apnea living at high altitude.

Purpose: Repetitive obstruction of larynx during sleep can lead to daytime pulmonary hypertension and alterations in right ventricular morphology and function in a small fraction of obstructive sleep apnea syndrome (OSAS) patients. Environmental effects, particularly high altitude, can modify the effects of OSAS on pulmonary circulation, since altitude-related hypoxia is related with pulmonary vasoconstriction. This potential interaction, however, was not investigated in previous studies.

Accelerated hypertension after venlafaxine usage.

Venlafaxine is the first antidepressant that acts via inhibiting serotonin and noradrenaline reuptake. Hypertension is observed in doses exceeding 300 mg/day and is the most feared complication. We report a patient with accelerated hypertension after venlafaxine use observed at a dose of 150 mg/day.

Assessment of right ventricular geometry and mechanics in chronic obstructive pulmonary disease patients living at high altitude.

Degree of increase in pulmonary artery pressure (PAP) and adaptive responses in right ventricular morphology and mechanics play an important role in the prognosis of chronic obstructive pulmonary disease (COPD) patients. Three dimensional echocardiography and deformation imaging are recent advancements in echocardiography that allow more through assessment of right ventricle. We aimed to investigate right ventricular geometry and mechanics in a stable COPD population living at moderately high altitude.

[Percutaneous closure of secundum atrial septal defects in pediatric and adult patients: short- and mid-term follow-up results].

Objectives: We aimed to evaluate the short- and mid-term results of patients with atrial septal defect (ASD) who were treated with percutaneous closure.

Study Design: Seventy-nine patients with secundum ASD (54 female and 25 male; mean age 26.2±17.

Idiopathıc pulmonary artery aneurysm.

Pulmonary artery aneurysms are rare pathologic conditions of the thoracic cavity. The ıdiopathic form of the disease is reported very rarely. We report the case of a 16-year-old girl with idiopathic pulmonary artery aneurysm with surface rendered 3-dimensional images of 64-slice computed tomography.

Right ventricular morphology and function in chronic obstructive pulmonary disease patients living at high altitude.

Introduction: Pulmonary vasculature is affected in patients with chronic pulmonary obstructive disease (COPD). As a result of increased pulmonary resistance, right ventricular morphology and function are altered in COPD patients. High altitude and related hypoxia causes pulmonary vasoconstriction, thereby affecting the right ventricle.

Prevalence of mitral valve prolapse in residents living at moderately high altitude.

Objective: Prolapse of mitral valve leaflets is a frequent disorder and the most common cause of severe mitral regurgitation in western countries. However, little is known about the effects of altitude on mitral valve prolapse. We studied the prevalence and echocardiographic characteristics of mitral valve prolapse at moderately high altitude and sea level.

The modification of serum lipids after acute coronary syndrome and importance in clinical practice.

Atherosclerosis is a pathology characterized by low-grade vascular inflammation rather than a mere accumulation of lipids. Inflammation is central at all stages of atherosclerosis. Acute coronary syndrome significantly affects the concentration and composition of the lipids and lipoproteins in plasma.

Thrombus at ostium of coronary sinus discovered during evaluation for cardiac resynchronization therapy.

A 50-year-old male patient with dilated cardiomyopathy was evaluated for cardiac resynchronization therapy. A transthoracic echocardiogram revealed a mass in close proximity to the coronary sinus ostium.The mass was considered to be a thrombus and found to have disappeared at the repeat echocardiogram performed following a month of anticoagulation therapy with warfarin.

Tombstoning ST-Elevation Myocardial Infarction.

Tombstoning ST elevation myocardial infarction can be described as a STEMI characterized by tombstoning ST-segment elevation. This myocardial infarction is associated with extensive myocardial damage, reduced left ventricle function, serious hospital complications and poor prognosis. Tombstoning ECG pattern is a notion beyond morphological difference and is associated with more serious clinical results.

The relationship between T-wave polarity and clinical as well as angiographic findings in the early stage of acute myocardial infarction.

Background: Restoration of a positive T-wave in the chronic stage of myocardial infarction (MI) is usually seen in patients with a non-Q-wave (non-transmural) MI, where a viable tissue is present. The causes and significance of a positive T-wave in the early phase of acute MI are not clear.

Aim: To investigate angiographic and clinical characteristics of patients with a positive T-wave in the early stage of acute MI.

Extent of coronary collateral vessel decrease with advanced age.

Objective: Animal experiments show that angiogenesis, responsible for the development of collaterals, impairs with increasing age. We retrospectively investigated the relationship between the extent of coronary collaterals and age in patients who had total occlusion in at least one of their epicardial coronary arteries.

Methods And Results: The records of 2160 consecutive patients who had undegone coronary angiography were examined.

Atherosclerotic involvement in patients with left or right dominant coronary circulation.

Background: There are variations in the anatomy of the coronary arteries in patients with left dominant circulation. The influence of anatomical variations in patients with left dominant circulation on coronary arteriosclerosis is not clear.

Aim: We investigated whether atherosclerotic involvement in patients with left dominant circulation differs from that in patients with right dominant circulation.

The influence of ambulatory blood pressure profile on left ventricular geometry.

Besides causing a hypertrophy in the left ventricle, hypertension results in a change in the geometry of the left ventricle. The blood pressure, which does not decrease enough during the night, leads to structural changes in the left ventricle. In this study, the influence of 24-hour blood pressure profile on the left ventricular geometry was examined.

Correlation between clinical findings and the "tombstoning" electrocardiographic pattern in patients with anterior wall acute myocardial infarction.

The tombstoning electrocardiographic pattern of a particular kind of ST-segment change, as observed in some patients during the early stages of acute myocardial infarction, is well known to be of prognostic value. However, little is understood of the causes and the relations of these changes. This study of 106 patients showed that in patients with tombstoning electrocardiographic patterns, infarction size is larger; left ventricular ejection fraction and preinfact angina are lower, and in-hospital complications are higher.

Influence of left ventricular geometry on regional systolic and diastolic function in patients with essential hypertension.

Objective: In essential hypertension, especially in concentric hypertrophy, global diastolic function is impaired. But, whether the left ventricular (LV) geometric pattern influences regional systolic and diastolic function or not, is unknown. This study was aimed to evaluate the influence of left ventricular geometric pattern on regional systolic and diastolic function in hypertensive patients.