Helicobacter pylori vacuolating cytotoxin genotypes and preneoplastic lesions or gastric cancer risk: a meta-analysis.

Background And Aim: Disease progression to gastric cancer (GC) occurs in only a small proportion of Helicobacter pylori (H.  pylori) infected patients. The bacterium vacuolating cytotoxin A (vacA) gene polymorphisms may determine the clinical consequences.

A comparison of answer retrieval through four evidence-based textbooks (ACP PIER, Essential Evidence Plus, First Consult, and UpToDate): a randomized controlled trial.

Background: The efficacy of bedside information products has not been properly evaluated, particularly in developing countries.

Aim: To compare four evidence-based textbooks by comparing efficacy of their use by clinical residents, as measured by the proportion of questions for which relevant answers could be obtained within 20 min, the time to reach the answer and user satisfaction.

Methods: One hundred and twelve residents were taught information mastery basics and were randomly allocated to four groups to use: (1) ACP PIER, (2) Essential Evidence Plus (formerly InfoRetriever), (3) First Consult, and (4) UpToDate.

The effect of captopril on progression of retinopathy in type 2 diabetes.

Background: Diabetic retinopathy is the leading cause of blindness in those of working age in the world. However, it is a preventable vision loss. According to current animal studies, it could be hypothesized that using angiotensin-converting enzyme inhibitors could play a crucial role as a protective factor in the progression of retinopathy in human.