Comparison between statistical and machine learning methods to detect the hematological indices with the greatest influence on elevated serum levels of low-density lipoprotein cholesterol.

Introduction: Elevated levels of low-density lipoprotein-cholesterol (LDL-C) is a significant risk factor for the development of cardiovascular diseases (CVD)s. Furthermore, studies have revealed an association between indices of the complete blood count (CBC) and dyslipidemia. We aimed to investigate the relationship between CBC parameters and serum levels of LDL.

Detection of Partially Structural Collapse Using Long-Term Small Displacement Data from Satellite Images.

The development of satellite sensors and interferometry synthetic aperture radar (InSAR) technology has enabled the exploitation of their benefits for long-term structural health monitoring (SHM). However, some restrictions cause this process to provide a small number of images leading to the problem of small data for SAR-based SHM. Conversely, the major challenge of the long-term monitoring of civil structures pertains to variations in their inherent properties by environmental and/or operational variability.

LPTD: a novel linear programming-based topology determination method for cryo-EM maps.

Summary: Topology determination is one of the most important intermediate steps toward building the atomic structure of proteins from their medium-resolution cryo-electron microscopy (cryo-EM) map. The main goal in the topology determination is to identify correct matches (i.e.

Three-Dimensional Graph Matching to Identify Secondary Structure Correspondence of Medium-Resolution Cryo-EM Density Maps.

Cryo-electron microscopy (cryo-EM) is a structural technique that has played a significant role in protein structure determination in recent years. Compared to the traditional methods of X-ray crystallography and NMR spectroscopy, cryo-EM is capable of producing images of much larger protein complexes. However, cryo-EM reconstructions are limited to medium-resolution (~4-10 Å) for some cases.

Solving the α-helix correspondence problem at medium-resolution Cryo-EM maps through modeling and 3D matching.

Cryo-electron microscopy (cryo-EM) has recently emerged as a prominent biophysical method for macromolecular structure determination. Many research efforts have been devoted to produce cryo-EM images, density maps, at near-atomic resolution. Despite many advances in technology, the resolution of the generated density maps may not be sufficiently adequate and informative to directly construct the atomic structure of proteins.