Cetuximab in metastatic squamous cell cancer of the skin: a Swiss case series.

Background: There is current evidence that non-melanoma skin cancers can be successfully treated with cetuximab.

Objective: To evaluate the use and efficacy of cetuximab (with or without radiotherapy) in a series of previously treated patients with metastatic squamous cell cancer of the skin (SCCS) in Switzerland.

Methods: We performed a retrospective analysis of six patients from four centers.

Pre- and posttransplant management of solid organ transplant recipients: risk-adjusted follow-up.

Solid organ transplant recipients (SOTR) have an increased risk of skin cancer due to their long-term immunosuppressive state. As the number of these patients is increasing, as well as their life expectancy, it is important to discuss the screening and management of skin cancer in this group of patients. The role of the dermatologist, in collaboration with the transplant team, is important both before transplantation, where patients are screened for skin lesions and the individual risk for skin cancer development is assessed, and after transplantation.

Contribution of herpesvirus specific CD8 T cells to anti-viral T cell response in humans.

Herpesviruses infect most humans. Their infections can be associated with pathological conditions and significant changes in T cell repertoire but evidences of symbiotic effects of herpesvirus latency have never been demonstrated. We tested the hypothesis that HCMV and EBV-specific CD8 T cells contribute to the heterologous anti-viral immune response.