Simultaneous Electrochemical Determination of Chlorzoxazone and Diclofenac on an Efficient Modified Glassy Carbon Electrode by Lanthanum Oxide@ Copper(I) Sulfide Composite.

This study synthesized a LaO@snowflake-like CuS composite to fabricate an electrochemical sensor for sensitively simultaneous detection of diclofenac and chlorzoxazone exploiting an easy hydrothermal approach, followed by analysis with XRD, FE-SEM, and EDX methods. According to voltammetric studies, the electrocatalytic diclofenac and chlorzoxazone oxidations on the electrode modified with LaO@SF-L CuS composites were increased, with greater oxidation currents, as well as the oxidation potential was significantly decreased due to synergetic impact of LaO@SF-L CuS composites when compared with the pure SF-L CuS NS-modified electrode. The differential pulse voltammetry findings showed wide straight lines (0.

Cardioprotective effect of vanillic acid against doxorubicin-induced cardiotoxicity in rat.

Background And Purpose: Doxorubicin (DOX) is an effective agent for the treatment of many neoplastic diseases. Cardiotoxicity is the major side effect of this drug and limits its use. Vanillic acid (VA) is a pharmaceutical compound from the phenolic acids family.