The effectiveness of gamma knife radiosurgery for the management of residual high-grade gliomas: A single institutional study.

High-grade gliomas (HGGs) are presently managed via surgical resection, external beam radiation therapy (EBRT), and chemotherapy. Although Gamma Knife radiosurgery (GKRS) is currently used to manage HGGs, it has not been considered standard care. This paper aims to compare the contribution of GKRS to clinical outcomes in patients in which gross total resection (GTR) cannot be achieved.

The importance of IDH1, ATRX and WT-1 mutations in glioblastoma.

Numerous genetic pathways associated with glioblastoma development have been identified. In this study, we investigated the prognostic significance of IDH1 and ATRX mutations and WT-1 and p53 expression in glioblastomas and that of surgical methods, radiotherapy and chemotherapy. 83 patients with glioblastomas were retrospectively evaluated.

Analysis of Survival of Patients with Brain Metastases According to Prognostic Indexes and Treatment Strategies.

Aim: To retrospectively evaluate the overall survival (OS) of patients with brain metastases (BMs) who had been treated with whole brain radiotherapy (WBRT) and Gamma Knife (GK) according to prognostic factors and prognostic index scores.

Material And Methods: The study included 91 patients with BMs who had been treated with WBRT and/or GK between 2014 and 2017. The patients with BMs were retrospectively evaluated regarding age, sex, Karnofsky Performance Status (KPS), recursive partitioning analysis (RPA) class, basic score for BM (BS-BM), Graded Prognostic Assessment (DS-GPA) index, primary tumour type, extracranial metastases, primary tumour control, number of BMs, and brain metastasectomy.

Psychosocial stressors, social support and socio-demographic variables as determinants of quality of life of Turkish breast cancer patients.

Purpose: The aim of the present study was to investigate the effects of psychosocial stressors, social support and socio-demographic variables on quality of life of breast cancer patients.

Tools And Methods: The study was conducted between December 2004 and May 2005 and included 101 patients, treated in the Oncology Departments of Ege and Pamukkale University Hospitals and Denizli State Hospital. Patients' demographic data were collected by questionnaire.

The preventive effect of vitamin D3 on radiation-induced hair toxicity in a rat model.

Our aim is to investigate the protective effect of vitamin D3 especially from radiation-induced hair toxicity. A model of skin radiation injury was developed and a single fraction of 20 Gy Gamma irradiation was applied to the right dorsal skin of fourteen rats. All animals were randomly divided into 2 groups: Group I: irradiation alone (n = 7) and Group II: irradiation and 0.

Psychiatric morbidity among cancer patients and awareness of illness.

A significant proportion of cancer patients experience psychiatric morbidity. Potential predictors of psychiatric morbidity include patient disease-related factors and factors relating to the patient's environment. The aim of this study was to investigate the prevalence of psychiatric morbidity and the relationship between the clinical or personal factors, especially psychiatric morbidity, and awareness of cancer diagnosis among a group of Turkish cancer patients.

[Psychiatric disorders in cancer patients and associated factors].

Objective: There is a high prevalence of psychiatric disorders, especially depression and anxiety, among cancer patients. If they are left untreated, especially depressive disorders, they may result in poor treatment compliance, increased hospital stays and reduced quality of life. The aim of this prospective study is to investigate the prevalence of psychiatric morbidity among cancer patients and the factors that predict psychiatric morbidity.

Radiotherapy in maxillary sinus carcinomas: evaluation of 79 cases.

Purpose: The aim of this study is to evaluate the outcome of patients with maxillary sinus carcinoma after radiotherapy regarding local control, prognostic factors and morbidity of treatment.

Materials And Methods: Between January 1983 and December 1996, 79 cases of maxillary sinus carcinoma without any evidence of distant metastases, were treated with radiotherapy.

Results: Fifty-two patients (65.