Synchronous anaplastic oligodendroglioma and carcinoma tongue: a rare association.

We present the case of a 45-year-old female patient who harbored two synchronous primary malignant neoplasms-an anaplastic oligodendroglioma of the right frontal lobe and a squamous cell carcinoma of the tongue. Both neoplasms were in advanced stage and carried a dismal prognosis. To the best of our knowledge, this is the first documentation in the english literature of such a presentation.

Psychosocial disorders in women undergoing postoperative radiation and chemotherapy for breast cancer in India.

Background: Breast cancer is the most common cancer in urban India, but no study has been carried out on psychosocial disorders in breast cancer patients.

Aims: The present study has been undertaken to evaluate behavioural and psychosocial impacts before and after treatment of women with breast cancer.

Settings And Design: The study was carried out in a reputed hospital in Delhi.

Spectroscopic study of Er:Sm doped barium fluorotellurite glass.

In this paper, we report the physical and spectroscopic properties of Er(3+), Sm(3+) and Er(3+):Sm(3+) ions codoped barium fluorotellurite (BFT) glasses. Different Stokes and anti-Stokes emissions were observed under 532 nm and 976 nm laser excitations. Energy transfer from Er(3+) ion to Sm(3+) ion was confirmed on the basis of luminescence intensity variation and decay curve analysis in both the cases.

Peripheral neuroectodermal tumor of the vulva: a case report.

Background: Peripheral neuroectodermal tumors arising from vulva are extremely rare; only 12 cases have been reported so far. These tumors belong to the Ewing sarcoma family of tumors. They occur in bones and variety of soft tissues of chest wall, pelvis, paravertebral region, and lower extremities.

Second-look hysteroscopy after antitubercular treatment in infertile women with genital tuberculosis undergoing in vitro fertilization.

Objectives: To assess the efficacy of antitubercular treatment on the uterine cavity in infertile women diagnosed with genital tuberculosis using second-look hysteroscopy.

Methods: A total of 70 women with genital tuberculosis who underwent second-look hysteroscopy were enrolled in the study. They were started on antitubercular drugs and followed up after 6 months of therapy with second-look hysteroscopy.

Umbilical surgical scar and vulval metastasis secondary to advanced cervical squamous cell carcinoma: a report of two cases.

Introduction: Association of cutaneous metastasis with cervical carcinoma is a rare finding, with only a few case reports in literature.

Case Report: Herein, we report a case of cervical squamous cell carcinoma, which later presented as widespread skin metastases on the surgical scar as an initial sign of recurrent disease.

Conclusion: In conclusion, incisional cutaneous and vulval metastasis is a rarity with cancer cervix and is considered as an ominous prognostic sign with a short survival after diagnosis.

Solubilization of poorly water-soluble drug carbamezapine in pluronic micelles: effect of molecular characteristics, temperature and added salt on the solubilizing capacity.

The solubilization of a poorly water-soluble antiepileptic drug, carbamazepine (CBZ), in a series of micelle-forming PEO-PPO-PEO block copolymers with combinations of blocks having different molecular weight was studied. The drug solubility and micelle-water partition coefficient (P) were determined using UV-vis spectroscopy. Dynamic light scattering on copolymer solutions was used to measure size and polydispersity of nanoaggregates.

Flare-up of genital tuberculosis following endometrial aspiration in a patient of generalized miliary tuberculosis.

Introduction: Genital tuberculosis is often neglected by health-care providers, but is an important cause of significant morbidity for the affected women.

Case Report: We report a rare case of tuberculosis (TB) flare in a 28-year-old nulliparous woman following endometrial aspiration (EA), which drained 30 ml pus. Following this, she developed high-grade fever with pain abdomen, guarding and rigidity.

Risk factors with breast cancer among women in Delhi.

Background: The incidence of breast cancer is on the rise in India, breast cancer is the second most common malignancy in Indian women.

Aim: The aim of this study was to find out the association of various risk factors with breast cancer among women in Delhi.

Settings And Design: This was a case-control study in Lok Nayak Hospital, Delhi.

Near-infrared imaging of injured tissue in living subjects using IR-820.

The unprecedented increase in preclinical studies necessitates high-throughput, inexpensive, and straightforward methods for evaluating diseased tissues. Near-infrared imaging of live subjects is a versatile, cost-effective technology that can be effectively used in a variety of pathologic conditions. We have characterized an inexpensive optoelectronic chemical, IR-820, as an infrared blood pool contrast agent to detect and quantify diseased tissue in live animals.

Biomarker system for studying muscle, stem cells, and cancer in vivo.

Bioluminescent reporter genes are sensitive in situ tools for following disease progression in preclinical models, albeit they are subject to scattering and absorption in deep tissues. We have generated a bicistronic Cre/LoxP reporter mouse line that pairs the expression of firefly luciferase with quantifiable expression of a human placental alkaline phosphatase that is secreted into the serum (SeAP). With the use of this dual-modality bioreporter with a novel, inducible Pax7-CreER line for tracking muscle satellite cells, we demonstrate the longitudinal kinetics of muscle stem cell turnover, accounting for a doubling of the signal from satellite cell and progeny every 3.

Metastatic ovarian tumour in patient of carcinoma stomach.

Krukenberg tumour (KT) is a metastatic ovarian tumour with primary usually seen in the gastrointestinal tract. Here we report the case of a 50-year old menopausal patient with gastric tumour presenting with solitary metastasis to the ovary within 5 months of primary gastric surgery, for which total abdominal hysterectomy with bilateral salpingo-oophorectomy was done. This case stresses the urgent need for early detection and surveillance of treatable tumours metastasising to the ovary.

Primitive neuroectodermal tumor of prostate.

Primitive neuroectodermal tumors (PNETs) are malignant proliferations of small, undifferentiated neuroectodermal cells occurring mainly in children and share the same reciprocal translocation between chromosomes 11 and 22 and the same patterns of biochemical and oncogene expression as osseus and extraosseus Ewing's sarcoma. Some PNETs occur in the brain, while others (the peripheral PNETs) occur in sites outside the brain, such as in the extremities, pelvis and the chest wall. They mostly originate in the chest, pelvis and retroperitoneum; in rare cases, occurrence in the head and neck area has also been seen.

Sex hormone binding globulin in breast cancer.

The present study was undertaken to determine the significance of sex hormone binding globulin, the major and specific binding protein for testosterone and estradiol, in breast cancer. Among breast cancer patients, lower serum levels of Sex hormone binding globulin and higher levels of testosterone were observed. Sex hormone binding globulin showed an inverse relationship with testosterone and total cholesterol, and a direct relation with HDL-cholesterol.

Control of Erysiphe pisi Causing Powdery Mildew of Pea (Pisum sativum) by Cashewnut (Anacardium occidentale) Shell Extract.

The effect of methanolic extract of cashewnut (Anacardium occidentale) shell extract was seen on conidial germination of Erysiphe pisi and powdery mildew development in pea (Pisum sativum). Maximum conidial germination inhibition of E. pisi on glass slides was observed at 300 ppm.

Optimization of volumetric computed tomography for skeletal analysis of model genetic organisms.

Forward and reverse genetics now allow researchers to understand embryonic and postnatal gene function in a broad range of species. Although some genetic mutations cause obvious morphological change, other mutations can be more subtle and, without adequate observation and quantification, might be overlooked. For the increasing number of genetic model organisms examined by the growing field of phenomics, standardized but sensitive methods for quantitative analysis need to be incorporated into routine practice to effectively acquire and analyze ever-increasing quantities of phenotypic data.

Socio-demographic profile of women undergoing abortion in a tertiary centre.

Introduction: Induced abortion is the most controversial area of family planning and it is often the most important method of fertility regulation by a community to control family size. Although abortion has been greatly liberalized, the annual number of legal abortions performed in India is 0.5 million of the annual estimated 6 million abortions.