Clinicopathological predictors of positive Ga-PSMA-11 PET/CT in PSA-only recurrence of localized prostate cancer following definitive therapy.

Objective: To demonstrate the effect of clinicopathological factors on Ga-PSMA-11 PET/CT positivity at the time of biochemical recurrence (BCR) of localized prostate cancer (PCa) following definitive therapy.

Methods: We retrospectively reviewed our institutional database for PCa patients who had BCR and subsequently underwent Ga-PSMA-11 PET/CT between April 2014 and February 2018. A total of 51 patients who were metastasis-free before PSMA imaging and previously treated with definitive therapy (radical prostatectomy or external beam radiotherapy) for localized disease (pT1c-T3b pN0-1 cM0) were included.