and are robust biomarkers for gingivitis and periodontitis in small dogs.

Introduction: Periodontal disease is one of the most common oral diseases in dogs and humans. It starts with gingivitis, a reversible condition, and progresses to an irreversible condition, periodontitis. Unlike humans, the etiology of periodontal disease in dogs has not been widely studied.

Dome-Structure Array from Pre-Strained Extendable Mesh for Tactile Sensing Without Crosstalk and Lateral Strain Interference.

Flexible tactile sensors have received significant attention for use in wearable applications such as robotics, human-machine interfaces, and health monitoring. However, conventional tactile sensors face challenges in accurately measuring pressure because vertical deformation is induced by Poisson's ratio in situations where lateral strain is applied. This study shows a strain-insensitive flexible tactile sensor array without the crosstalk effect using a highly stretchable mesh.

Surveillance of Norovirus in Nationwide Groundwater Sources in South Korea: A Comprehensive Five-Year Study.

Groundwater is an essential drinking water source for humans. However, improper groundwater management leads to fecal contamination and waterborne diseases caused by viral pathogens. Therefore, this study aimed to investigate norovirus (NoV) contamination by conducting nationwide monitoring over five years (2019-2023).

Assessment of Quadriceps Muscle in Advanced Knee Osteoarthritis and Correlation with Lower Limb Alignment.

: Despite extensive studies of the role of quadriceps and quadriceps/hamstring balance in knee osteoarthritis (OA), the roles of the vastus intermedius, medialis, and lateralis in OA remain unclear. The purpose of this study was to investigate the relationship of lower limb alignment and the ratio of the quadriceps femoris muscle to the knee extensor muscle. : This study included 50 patients with advanced knee OA (Kellgren/Lawrence grade of 3 or 4) and 25 healthy control persons between June 2021 and May 2022.

Clinical Course and Prognostic Factors in Non-Neovascular Age-Related Macular Degeneration with Subretinal Fluid.

Purpose: To investigate the clinical course and prognostic factors of age-related macular degeneration (AMD) without macular neovascularization (MNV) in patients presenting with pigment epithelial detachment (PED) and the associated subretinal fluid (SRF).

Methods: Morphological characteristics of spectral-domain optical coherence tomography images were analyzed to determine anatomic outcomes. Factors associated with the progression to late AMD, defined as complete retinal pigment epithelium and outer retinal atrophy (cRORA) or MNV, were investigated.

Improvement of Late-Onset Hypogonadism Symptoms of Fermented Extract in TM3 Leydig and TM4 Sertoli Cells.

Background/objectives: Late-onset hypogonadism (LOH), characterized by declining testosterone levels with age, negatively affects the health of men, causing physical, psychological, and sexual dysfunction. Conventional testosterone replacement therapies have side effects, which has led to interest in natural alternatives. We investigated the effects of a standardized fermented extract (FME) on oxidative stress-induced damage in TM3 Leydig and TM4 Sertoli cells.

"She deserves the best. So how can I feed her the best?" Complementary food introduction practices among young mothers with a history of child maltreatment.

Purpose: To explore the practices, experiences, and needs of young mothers with a history of maltreatment who are introducing their children to complementary foods.

Design And Methods: In-depth interviews (n = 9) were conducted with young mothers (19-23 yrs) who had childhood histories of abuse and neglect (maltreatment). Interviews were transcribed verbatim and analyzed using a five-step thematic analysis approach.

Concurrent validity and test reliability of the deep learning markerless motion capture system during the overhead squat.

Marker-based optical motion capture systems have been used as a cardinal vehicle to probe and understand the underpinning mechanism of human posture and movement, but it is time-consuming for complex and delicate data acquisition and analysis, labor-intensive with highly trained operators. To mitigate such inherent issues, we developed an accurate and usable (5-min data collection and processing) deep-learning-based 3-Dimensional markerless motion capture system called "Ergo", designed for use in ecological digital healthcare environments. We investigated the concurrent validity and the test-retest reliability of the Ergo system measurement's whole body joint kinematics (time series joint angles and peak joint angles) data by comparing it with a standard marker-based motion capture system recorded during an overhead squat movement.

Comprehensive Study of Antibiotic Resistance in spp.: Comparison of Influents and Effluents of Wastewater Treatment Plants.

: The spread of antibiotic resistance, particularly through spp., in wastewater treatment plants (WWTPs) poses significant public health risks. Given that research on antibiotic-resistant enterococci and their antibiotic-resistance genes in aquatic environments is limited, we evaluated the role of spp.

Development of a novel complex inflammatory bowel disease mouse model: Reproducing human inflammatory bowel disease etiologies in mice.

Inflammatory bowel disease (IBD), caused by environmental factors associated with the host's genetic traits, is represented by Crohn's disease and ulcerative colitis. Despite the increasing number of patients with IBD, the current treatment is limited to symptomatic therapy. A complex IBD model mimicking the human IBD etiology is required to overcome this limitation.

Corrigendum: Cellular heterogeneity and plasticity during NAFLD progression.

[This corrects the article DOI: 10.3389/fmolb.2023.

Lactate utilization in Lace1 knockout mice promotes browning of inguinal white adipose tissue.

Recent studies have focused on identifying novel genes involved in the browning process of inguinal white adipose tissue (iWAT). In this context, we propose that the mitochondrial ATPase gene lactation elevated 1 (Lace1) utilizes lactate to regulate the browning capacity of iWAT, specifically in response to challenge with CL-316,243 (CL), a beta3-adrenergic receptor (β3-AR) agonist. The mice were injected with CL over a span of 3 days and exposed to cold temperatures (4-6 °C) for 1 week.

Nationwide trends and incidence of blindness in patients with diabetic retinopathy identified using an age-period-cohort analysis.

Objectives: To estimate the epidemiologic trends of blindness in patients with diabetic retinopathy (DR) and investigate the age-, period-, and cohort-specific effects on blindness.

Methods: A total of 2.5 million patients with DR aged 20 years or older were included from the Korean National Health Claims database from 2005 to 2019.

Factors Affecting Delirium Care Core Competency Among Nurses: A Descriptive Correlational Study.

Nurses require optimal competency to deliver safe and high-quality care to patients with delirium. However, the factors influencing delirium care core competency remain unclear. This study aims to investigate the factors influencing core competency in delirium care among nurses.

Dual-Seed Strategy for High-Performance Anode-Less All-Solid-State Batteries.

Interest in all-solid-state batteries (ASSBs), particularly the anode-less type, has grown alongside the expansion of the electric vehicle (EV) market, because they offer advantages in terms of their energy density and manufacturing cost. However, in most anode-less ASSBs, the anode is covered by a protective layer to ensure stable lithium (Li) deposition, thus requiring high temperatures to ensure adequate Li ion diffusion kinetics through the protective layer. This study proposes a dual-seed protective layer consisting of silver (Ag) and zinc oxide (ZnO) nanoparticles for sulfide-based anode-less ASSBs.

Significantly improving zero-shot X-ray pathology classification via fine-tuning pre-trained image-text encoders.

Deep neural networks are increasingly used in medical imaging for tasks such as pathological classification, but they face challenges due to the scarcity of high-quality, expert-labeled training data. Recent efforts have utilized pre-trained contrastive image-text models like CLIP, adapting them for medical use by fine-tuning the model with chest X-ray images and corresponding reports for zero-shot pathology classification, thus eliminating the need for pathology-specific annotations. However, most studies continue to use the same contrastive learning objectives as in the general domain, overlooking the multi-labeled nature of medical image-report pairs.

Clinical effect of rehabilitation after distal radius fracture surgery using a wearable device: A comparative prospective cohort study.

Background: Appropriate postoperative rehabilitation of distal radius fractures is essential for early recovery and pain management, but may be limited by medical staff and equipment availability and costs. Home-based training or wearable devices provide an alternative.

Objectives: To assess use of a wearable device and home-based training for rehabilitation after distal radius fracture surgery.

Long-Term Results of Meniscus Allograft Transplantation With Bone Fixation Show Improved Outcomes but Progression of Joint Space Narrowing, Osteoarthritis, and Cartilage Degeneration.

Purpose: To investigate the clinical and objective outcomes of meniscal allograft transplantation (MAT) using bone fixation in patients after a minimum follow-up duration of 15 years and to compare the demographic factors and allograft status between patients who experienced progression of osteoarthritis and those who did not.

Methods: Consecutive patients who underwent primary MAT between December 1996 and January 2008 were reviewed retrospectively. The inclusion criterion was primary MAT with a minimum follow-up duration of 15 years.

Efficacy and safety of SKCPT in patients with knee osteoarthritis: A multicenter, randomized, double-blinded, active-controlled phase III clinical trial.

Ethnopharmacological Relevance: Osteoarthritis (OA) is the most prevalent type of arthritis worldwide and a leading cause of years lost to pain and disability. Among the current pharmacological treatments for OA, symptomatic slow-acting drugs for OA (SYSADOA) induce pain relief and aim to improve joint function by relieving inflammation while causing fewer gastrointestinal and cardiovascular adverse events than non-steroidal anti-inflammatory drugs (NSAIDs). SKCPT is a herbal SYSADOA formulated from Clematis mandshurica, Trichosanthes kirilowii, and Prunella vulgaris powdered extracts.

Extremely durable electrical impedance tomography-based soft and ultrathin wearable e-skin for three-dimensional tactile interfaces.

In the rapidly evolving field of human-machine interfaces (HMIs), high-resolution wearable electronic skin (e-skin) is essential for user interaction. However, traditional array-structured tactile interfaces require increased number of interconnects, while soft material-based computational methods have limited functionalities. Here, we introduce a thin and soft e-skin for tactile interfaces, offering high mapping capabilities through electrical impedance tomography (EIT).

Prediction of Axial Length From Macular Optical Coherence Tomography Using Deep Learning Model.

Purpose: The purpose of this study was to develop a deep learning model for predicting the axial length (AL) of eyes using optical coherence tomography (OCT) images.

Methods: We retrospectively included patients with AL measurements and OCT images taken within 3 months. We utilized a 5-fold cross-validation with the ResNet-152 architecture, incorporating horizontal OCT images, vertical OCT images, and dual-input images.