Publications by authors named "Badih Kabchi"

Article Synopsis
  • Researchers wanted to find out if they could identify patients at high risk for pneumonia in hospitals in Europe, like they did in the U.S.
  • They studied adults in intensive care units across 7 European hospitals to see how many developed pneumonia and if they could join tests for new antibiotics.
  • The results showed that more European patients got pneumonia compared to those in the U.S., but fewer of them were treated with antibiotics, which might affect their ability to join important medical trials.
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Intravenous (i.v.) minocycline is increasingly used to treat infections caused by multidrug-resistant (MDR) Despite its being approved nearly 50 years ago, published information on its pharmacokinetic (PK) profile is limited.

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Article Synopsis
  • Pneumonia is the top infection-related cause of death, and identifying high-risk patients using clinical criteria can improve prevention and treatment strategies in hospitals.
  • A study focused on patients in ICUs across 28 US hospitals found that 32% of high-risk patients were treated for potential nosocomial pneumonia, with 37% diagnosed with it.
  • Factors like trauma diagnosis, aspiration risk, enteral nutrition, and recent antibacterial treatment increased the odds of developing nosocomial pneumonia in these patients.
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Background: Penicillin skin testing (PST) is a simple and reliable way of diagnosing penicillin allergy. After being off the market for 4 years, penicilloyl-polylysine was reintroduced in 2009 as PRE-PEN. We describe the negative predictive value (NPV) of PST and the impact on antibiotic selection in a sample of hospitalized patients with a reported history of penicillin allergy.

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