A pilot study on craving and its relationship to self-ratings of depression and anxiety in prescription opioid use disorder.

The role of craving in opioid use disorder (OUD) has been well established with respect to heroin but less so with prescription opioids. This pilot study, conducted in 18 treatment-seeking patients with prescription OUD and 18 healthy volunteers, assessed spontaneous (in the moment) and cue-induced craving and their relationship to depression and anxiety. Patients (vs.

The multicomponent model of working memory fifty years on.

We provide a broad overview of our original investigation of working memory; how the multicomponent model followed from our use of a dissociative methodology; and our intention that it should be simple, robust, and applicable. We describe how subsequent development of the model has increased its scope, depth, and applications while at the same time retaining its core features. Comparisons with the growing number of alternative models suggest agreement on the basic phenomena to be explained and more similarities than differences.

Diabetes as a risk factor for tuberculosis disease.

Background: Tuberculosis (TB) is amongst the leading causes of death from an infectious disease, with an estimated 1.3 million deaths from TB in 2022. Approximately 25% of the global population is estimated to be infected with the TB bacterium, giving rise to 10.

Influence of degree of learning on rate of forgetting of tonal sequences.

Initial performance is frequently equated in studies that compare forgetting rates across groups. However, since the encoding capacity of different groups can be different, some procedures to match initial degree of learning need to be implemented, adding confounding variables such as longer exposures to the material, which would create memories of a different age. Slamecka and McElree Journal of Experimental Psychology: Learning, Memory, and Cognition, 9, 384-397, (1983) and our previous work found that the rate of forgetting was independent from initial degree of learning using verbal material.

Undernutrition as a risk factor for tuberculosis disease.

Background: Tuberculosis (TB) is a leading cause of mortality due to an infectious disease, with an estimated 1.6 million deaths due to TB in 2022. Approximately 25% of the global population has TB infection, giving rise to 10.

Visual working memory phenomena based on categorical tasks replicate using a continuous measure: A simple interpretation and some methodological considerations.

An increasingly popular method for investigating visuospatial working memory assumes stored features of objects such as color and orientation vary along continua subject to internal noise. It adapts the stimulus adjustment procedure from perceptual psychophysics to assess the precision with which stored features are represented in memory. This contrasts with methods using discrete, categorical measures of feature retention.

Rate of forgetting is independent from initial degree of learning across different age groups.

It is well established that the more we learn, the more we remember. It is also known that our ability to acquire new information changes with age. An important remaining issue for debate is whether the rate of forgetting depends on initial degree of learning.

TB preventive treatment among pregnant women with HIV.

The WHO recommends TB preventive treatment (TPT) for people living with HIV, including pregnant women. Uptake of this policy recommendation in this subpopulation and country alignment with WHO guidance is unclear. We conducted a policy review in 38 WHO high TB and TB-HIV burden countries to assess if the uptake of TPT policy among pregnant women living with HIV was in line with the WHO´s 2018 Updated and Consolidated Guidelines for Programmatic Management for LTBI.

Intact high-resolution working memory binding in a patient with developmental amnesia and selective hippocampal damage.

Debate continues regarding the possible role of the hippocampus across short-term and working memory tasks. The current study examined the possibility of a hippocampal contribution to precise, high-resolution cognition and conjunctive memory. We administered visual working memory tasks featuring a continuous response component to a well-established developmental amnesic patient with relatively selective bilateral hippocampal damage (Jon) and healthy controls.

The effect of selective retrieval practice on forgetting rates in younger and older adults.

Recent findings demonstrate that selective retrieval practice (SRP), specifically the retrieval of subparts of material, not just retrieval of the entire encoded material, can enhance later memory performance. We present two experiments that investigated whether SRP enhances memory performance among older adults. We also examined to what extent this effect is enhanced by the level of integration of the studied material.

Interventions to improve linkage along the HIV-tuberculosis care cascades in low- and middle-income countries: A systematic review and meta-analysis.

Introduction: In support of global targets to end HIV/AIDS and tuberculosis (TB) by 2030, we reviewed interventions aiming to improve TB case-detection and anti-TB treatment among people living with HIV (PLHIV) and HIV testing and antiretroviral treatment initiation among people with TB disease in low- and middle-income countries (LMICs).

Methods: We conducted a systematic review of comparative (quasi-)experimental interventional studies published in Medline or EMBASE between January 2003-July 2021. We performed random-effects effect meta-analyses (DerSimonian and Laird method) for interventions that were homogenous (based on intervention descriptions); for others we narratively synthesized the intervention effect.

Forgetting rates of gist and peripheral episodic details in prose recall.

In a seminal study, Slamecka and McElree showed that the degree of initial learning of verbal material affected the intercepts but not the slopes of forgetting curves. However, more recent work has reported that memories for central events (gist) and memory for secondary details (peripheral) were forgotten at different rates over periods of days, with gist memory retained more consistently over time than details. The present experiments aimed to investigate whether qualitatively different types of memory scoring (gist vs.

Tuberculosis screening among HIV-positive inpatients: a systematic review and individual participant data meta-analysis.

Background: Since 2011, WHO has recommended that HIV-positive inpatients be routinely screened for tuberculosis with the WHO four-symptom screen (W4SS) and, if screened positive, receive a molecular WHO-recommended rapid diagnostic test (eg, Xpert MTB/RIF [Xpert] assay). To inform updated WHO tuberculosis screening guidelines, we conducted a systematic review and individual participant data meta-analysis to assess the performance of W4SS and alternative screening tests to guide Xpert testing and compare the diagnostic accuracy of the WHO Xpert algorithm (ie, W4SS followed by Xpert) with Xpert for all HIV-positive inpatients.

Methods: We searched MEDLINE, Embase, and Cochrane Library from Jan 1, 2011, to March 1, 2020, for studies of adult and adolescent HIV-positive inpatients enrolled regardless of tuberculosis signs and symptoms.

Resting State EEG Activity Related to Impulsivity in People with Prescription Opioid Use Disorder.

Previous studies on EEG activity in prescription opioid use disorder (OUD) have reported neuronal dysfunction related to heroin use, most consistently reflected by increases in β-brain oscillations. As similar research has yet to examine EEG associated with non-medical use of prescription opioid and as inhibitory deficits are associated with OUD, this pilot study compared quantitative EEGs of 18 patients with prescription OUD and 18 healthy volunteers and assessed relationships between oscillatory activity and impulsivity with the Barratt Impulsiveness Scale (BIS-11). Spectral EEGs showed greater amplitude density in β, β, and β frequencies across frontal, temporal-central and posterior recording areas in patients.

Translating words into actions in working memory: The role of spatial-motoric coding.

Research from a working memory perspective on the encoding and temporary maintenance of sequential instructions has established a consistent advantage for enacted over verbal recall. This is thought to reflect action planning for anticipated movements at the response phase. We describe five experiments investigating this, comparing verbal and enacted recall of a series of action-object pairings under different potentially disruptive concurrent task conditions, all requiring repetitive movements.

Rate of forgetting is independent of initial degree of learning.

It is commonly assumed that the rate of forgetting depends on initial degree of learning. Hence, comparison of forgetting across groups is usually carried out equating initial performance. However, these matching procedures add confounding variables.

Developing the Concept of Working Memory: The Role of Neuropsychology1.

The evolution of the concept of a multicomponent working memory is described with particular reference to the contribution from neuropsychology. Early evidence from patients with the classic amnesic syndrome, together with others showing the opposite deficit of impaired short-term but preserved long-term memory argued strongly for a separation between long- and short-term memory systems. Simulation of the short-term deficit in healthy participants using a dual task approach suggested the need to assume a three component system serving as a multi-purpose working memory comprising an overall attentional control system, the Central Executive, aided by separable temporary buffer stores for phonological and visuospatial information.