[Epidemiologic and microbiological aspects of mycobacteriosis in Slovakia--Mycobacterium szulgai].

The first case of mycobacteriosis caused by M. szulgai in the territory of Czechoslovakia was discovered in the year 1979 in southern Slovakia and was published in our and foreign literature in the year 1981. The purpose of this investigation is to describe the epidemiological situation of the diseases caused by M.

[Epidemiologic and microbiologic aspects of mycobacteriosis in Slovakia--M. xenopi].

The first mycobacterioses caused by M. xenopi in Slovakia were discovered in the year 1979. Gradually they became the most often occurring mycobacterioses caused by facultative pathogenic mycobacteria.

[Epidemiologic and microbiologic aspects of mycobacteriosis in Slovakia. M. fortuitum].

The purpose of this paper is to confront the knowledge about the epidemiology of this disease abroad with information obtained in Slovakia. The methodology of this paper is based upon surveillance of tuberculosis as applied on mycobacterioses. Pulmonary infections caused by M.

[Epidemiologic and microbiologic aspects of mycobacteriosis in Slovakia].

Mycobacterioses are diseases caused by mycobacteria other than those that induce the classical tuberculosis: M. tbc (previously to as "human" type) and M. bovis (previously to as "bovine" type of mycobacteria).

[Epidemiologic and microbiologic aspects of mycobacteriosis in Slovakia. M. avium complex].

Background: Mycobacteria belonging to M. Avium Complex (MAC) are strains very similar in structure and biochemistry but very different from the point of serology.

Objectives: They are divided into 28 serotypes.

Surveillance of tuberculosis caused by Mycobacterium bovis in Slovakia.

The elimination of tuberculosis (TB) among cattle was claimed in Czecho-Slovakia in the middle of the sixties. Experiences from some countries which eliminated TB among cattle earlier than Czecho-Slovakia indicated a sporadic occurrence of TB caused by M. bovis.

[Activity of the Department of Clinical Epidemiology during the 25 years of its existence in the clinical arena].

Twenty-five years ago in the Institute of Tuberculosis and Respiratory Diseases in Bratislava was created a Department of Clinical Epidemiology. It was the first department to bear this title. The authors analyze the activity of this department.

New trends of postgraduate education in public health in Slovakia (the first experiences of the school of public health in Bratislava).

The School of Public Health (SPH) in Bratislava was established on 1 July 1991, as an organisational unit of the Post-graduate Medical School, directly subordinated to the Ministry of Health of the Slovak Republic. The SPH performs both postgraduate and continuing education of specialists in individual public health branches. It participates in the research activities within the field of public health.

Medical teacher and his pedagogical training (experience with Bratislavian system of training the assistants for pedagogical activity in postgraduate education of physicians and pharmacists).

System of training the medical teachers for pedagogical activity, used in the Institute for Postgraduate Education of Physicians and Pharmacists (IPEPP) in Bratislava, have not had long tradition as yet. We do not want this training to be understood as universal instruction to prepare the assistants for pedagogical activity, which is in a final consequence always dependent on the concrete conditions and social needs. It should serve as information on one of the possibilities to secure the systematic training of medical teachers for pedagogical activity in postgraduate education of physicians and pharmacists.

Combined treatment of patients with lung carcinoma. (Preliminary results assembled in international cooperative investigation).

The authors submit information on the preliminary results of combined treatment of patients with carcinoma of the lungs (epidermoid, adenocarcinoma, large-cell and combined carcinoma). The patients were classified, consistents with the protocol of the study, into two basic groups, each of which was sub-divided at random into two sub-groups. In the first group of 25 patients 9 were subjected to preoperative radiotherapy--2 000 rad (Co60) and 16 patients were operated without previous radiotherapy.

Application of gibberelic acid (GA) alone or together wih cytostatics in treatment of lung cancer.

Gibberelic acid (GA) was used alone or in combination with cytostatics (Vincristine, Cyclophosphamide, HN3), surgical treatment or radiotherapy, in treatment of 65 patients with lung cancer. The patinets were followed up from the end of 1972 until the end of 1977. It was found that the administration of GA, at the given doses, did not cause toxic effects in treated patients and it improved for shorter or longer period of time some metabolic functions and activity of hemopoiesis.

Epidemiological and clinical significances of urolithiasis in childhood.

An epidemiological and clinical study of a sample of 105 children with urolithiasis treated in the period 1965-1974 in a defined population of children revealed a decrease in the rate of incidence of this disease in a municipal infant population with high-ranking care for their health. Serious forms of urolithiasis are on the decrease. There is a higher rate of incidence in schoolboys and schoolgirls, the latter being more often involved than boys.

Early detection of airway abnormalities in a selected group of population.

Functional data were collected from 5,746 males from a country region, whose ages ranged from 14 to 65 years. Out of this population we excluded a group of 466 males (9%) who had abnormal results of traditional pulmonary function screening tests (FVC less than 80% reference values or FEV1% FVC less than 70%) and chose a group of 1,092 males (19%) with normal values for the above two parameters but with abnormal forced mid-expiratory flow. In randomly selected persons of the second group we found frequency dependent dynamic compliance (100%), abnormal maximum expiratory flow at 25% of vital capacity (98%), increased residual volume (76%), decreased maximum expiratory flow at 50% of vital capacity (67%), and increased closing capacity (57%); on the contrary static complicane and airway resistance were normal.

Investigation of the inhibitory activity of some mycobacterial strains on growth of the intratracheally transplanted Deals' sarcoma in guinea pigs.

In this paper the authors describe and analyse results that they obtained by infection of the guinea pig organism carried out by subcutaneous or intratracheal application with five mycobacterial strains, namely Myco bovis BCG-Praha, Myco the H37Ra, Myco Kansasii, Myco fortuitum and Myco smegmatis. At predetermined time intervals following subcutaneously or intratracheally performed infection (on 7th, 16th, 28th and 56th day after infection) transplantation of a Deals' guinea pig sarcoma cell suspension was carried out in guinea pigs by the intraltracheal route. As it appears from the results gained the applied mycobacteria exhibit a partial inhibition of growth od Deals' guinea pig sarcoma cells of different character.