Species and organ dependence of PCB contamination in fish, foxes, roe deer, and humans.

According to previous experimental results, PCBs are deposited in muscle fat in animals and in humans, although they also reach the brain, the liver, and the lungs. The aim of the present study was to determine the concentrations of the so-called "indicator PCBs" (PCB nos. 28, 52, 101, 138, 153, 180), as described by the German ordinance for maximum concentrations of contaminants in foodstuffs, in muscle tissue, liver, and brain of four different species: fish, fox, roe deer, and humans, all exposed to PCBs directly in their environment.

Polychlorinated biphenyl congeners in foxes in Germany from 1983 to 1991.

Red foxes served as a biological indicator for the temporal development of environmental contamination with polychlorinated biphenyls (PCB). The concentration of PCB congeners nos. 28, 49, 52, 101, 138, 153, and 180 were analyzed in the body fat of 80 foxes (Canis vulpes) from Germany.

[Therapy of orthostatic dysregulation with gepefrin. Study with continuous telemetric blood pressure monitoring].

The action of the new pressor agent gepefrine (D form of 3-hydroxyphenyl-2-aminopropan) was evaluated in 16 patients with typical clinical symptoms of orthostatic adjustment disorders. The blood pressure measured in the brachial artery (percutaneous puncture and catheterisation according to the Seldinger technique) and the electrocardiogram were transmitted by telemetry and continuously documented under standard conditions at rest, on standing and during a step test. One hour after oral administration of 30 mg or 45 mg gepefrine the blood pressure increased significantly at rest and more markedly on standing and during the step test.

[Long term experiences with a solid spironolactone-furosemide combination in heart insufficiency and hypertension].

Nineteen ambulant patients in cardiac insufficiency stages III to IV, eleven of them concomitantly presenting hypertension, were treated with Osyrol 50-Lasix for a period of three months. With a maintenance dose consisting on average of one capsule Osyrol 50-Lasix daily, effective and reliable elimination of edema and adequate recompensation of the heart was achieved by way of reduction of the body weight, decrease in ankle circumference, congestion of the liver and improvement of dyspnoea. In the eleven patients with hypertension grade I, the systolic and diastolic blood pressure was normalized under Osyrol 50-Lasix medication, whilst the blood pressure values of normotensive patients were practically unchanged.

[Hemodynamic effects of aldosterone antagonists in patients with mitral stenosis (author's transl)].

In 12 patients with mitral stenosis of a severity that surgery was required, some hemodynamic parameters after intravenous injection of 400 mg Kaliumcanrenoat were studied. The hemodynamic changes were noted after 15 min and reached maximal values after 60 min. The increased values of pulmonary wedge, pulmonary artery and right atrial pressures were significantly reduced and the cardiac index and stroke volume index augmented, with unchanged systemic arterial pressure.

[Quantitative analysis of the peripheral arterial blood pressure curve in patients with peripheral obstructive cardiomyopathy after premature beats (author's transl)].

Changes of the brachial artery pressure curves after mechanically released extrasystoles were investigated in 20 patients suffering from hypertrophic obstructive cardiomyopathy. Diagnosis was confirmed by heart catheterisation and laevocardiography. At the average, the postextrasystolic beat showed a more pronounced reduction of the pressure at the systolic dip and the second systolic peak (19.

[Continuous monitoring of direct intra-arterial blood pressure in normal and preeclamptic pregnancies (author's transl)].

Blood pressure was monitored continuously and intraarteriously for 24 hours in healthy and pre-eclampsia pregnant women. The monitoring system almost excluded sources of error. The 24-hours-rhythm revealed a blood pressure decrease of about 20 Torr systolically and diastolically between 2.

[Telemetry of blood pressure in healthy subjects and patients with tachycardia and hypertension under Prindolol treatment].

The effect of 0.4 mg i.v.

[Hemodynamics after prindolol and digitalis in acute myocardial infarction (author's transl)].

In 20 patients with acute myocardial infarction hemodynamic controls were performed after digitalisation and following i.v. injection of 0,4 mg of Prindolol.

[The antiarrhythmic effect of digitalis in acute myocardial infarction with cardiac failure (author's transl)].

In 59 digitalized and 3 non digitalized patients the effect of digitalis during the 1st to 4th days after transmural myocardial infarction was controlled. Rhythm disturbances in acute myocardial infarction may arise secondary to a complicating cardiac failure and may be influenced by digitalis. In 9 of 17 cases (53 p.

[Digitalization for acute myocardial infarction: haemodynamic changes in patients with heart failure at rest (author's transl)].

Haemodynamic changes after intravenous administration of 0.4 mg beta-methyldigoxin or 0.4 mg digoxin daily were measured on the first to fourth day in 42 patients in heart failure after onset of transmural myocardial infarction.

[Hemodynamic evaluation of cardiac insufficiency in the acute stage of myocardial infarct].

In 70 patients hemodynamic controls were preformed during the first 4 days after acute myocardial infarction. A sufficient regulation of heart function and the circulation at rest was accepted with the following conditions: pulmonary artery wedge pressure less than or equal to 13mm Hg, mean right atrial pressure less than or equal to 6 mm Hg, mean systemic arterial pressure greater than 70 mm Hg, cardiac index greater than 2.51/min/m2 and stroke index greater than 25 ml/m2.