Publications by authors named "Baburao Kancharla"
Article Synopsis
- The study aimed to evaluate and compare two methods of assessing respiratory safety in rats to determine the best approach for identifying drug-induced respiratory issues in preclinical research.
- Different plethysmography techniques (head out and whole body) were utilized to measure parameters like respiratory rate and tidal volume, specifically testing the effects of drugs like theophylline, chlordiazepoxide, and propranolol.
- Results indicated that head out plethysmography might provide more reliable data on ventilatory function, although additional invasive methods may be necessary for comprehensive airway function assessment.