Effect of supplementation of distillers' dried grain with solubles (DDGS) to a straw-based diet on performance, carcass characteristics, and meat quality in Nellore ram lambs.

Distillers dried grains with solubles (DDGS), a byproduct of ethanol production, has gained recognition as a viable alternative feed supplement for ram lambs because of its nutritional profile and cost-effectiveness. This study evaluated the effect of supplementing straw-based diets with different levels of DDGS on the growth performance and economic viability of growing ram lambs. A total of 24 ram lambs (16.

Impact of COVID-19 pandemic on the mental health status among general masses: An in-deep analysis of the worst "hitters" of COVID-19 pandemic.

Background: A plethora of studies have reported the adverse psychiatric outcomes among the general masses during the COVID-19 pandemic; however, not much data is available in relation to the Indian population from this perspective. The aim of the present study was to investigate the impact of the COVID-19 pandemic on the mental health status among the general masses in the Indian population.

Materials And Methods: The present study was planned in a cross-sectional study design between July 2020 and October 2021 in which a well-structured questionnaire, consisting of questions assessing the sociodemographic profile, while, also, specific questions related to the stress and anxiety-related variables, was used.

Vehicular pollution as the primary source of oxidative potential of PM in Bhubaneswar, a non-attainment city in eastern India.

We assessed the oxidative potential (OP) of PM ( = 230) using dithiothreitol (DTT) assay to identify the major emission sources in Bhubaneswar (20.20°N, 85.80°E), one of the non-attainment cities under the National Clean Air Program, situated on the eastern coast of India.

Factors Affecting Survival in Severe and Very Severe COPD after Admission in ICUs of Tertiary Care Centers of India (FAST COPD): Study Protocol for a Multicentric Cohort Study.

Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. However, there is a lack of comprehensive data from low- and middle-income countries (LMICs) regarding factors influencing COPD outcomes, particularly in regions where biomass exposure is prevalent.

Objective: The Factors Affecting Survival in Severe and Very Severe COPD Patients Admitted to Tertiary Centers of India (FAST) study aims to address this gap by evaluating factors impacting survival and exacerbation rates among COPD patients in LMICs like India, with a specific focus on biomass exposure, clinical phenotypes, and nutritional status in patients admitted to the Intensive Care Unit (ICU).

Anthropogenic sources and liquid water drive secondary organic aerosol formation over the eastern Himalaya.

Atmospheric aerosols have a serious impact on altering the radiation balance of the vulnerable Himalayan atmosphere. Organic aerosol (OA), one of the least resolved aerosol fractions in the Himalayas, constrain our competence to assess their climate impacts on the region. Here we investigate water-soluble OA molecules in PM samples collected from March to May 2019 at Lachung (27.

Traumatic Dental Injuries and their Association with Demographics and Other Predisposing Risk Factors in School Children Aged between 8-13 Years: A Descriptive, Cross-Sectional Study.

Background: Traumatic dental injuries are most commonly seen in school age children. This not only affects physical, but, also, the psychological and social well-being of a child. The aim of the present study was to assess the prevalence of traumatic dental injuries in school children aged between 8 and 13 years and their association with the demographics and other predisposing risk factors.

Change in precipitation pattern over South Asia in response to the trends in regional warming and free-tropospheric aerosol loading.

Spatial and temporal shifts in rainfall patterns over South Asia and the adjoining Seas during the pre-monsoon season have been observed over the past 2 decades from 2000 to 2019. Aerosol particles suspended above the boundary layer are a contributing factor to these changes. These particles not only alter cloud characteristics, but also diminish the lapse rate, thereby suppressing convective activity, leading to precipitation anomalies.

Bioactive constituents from Tinospora cordifolia (willd.): Isolation, synthesis and their immunomodulatory activity.

Traditional medicinal plants have been used for centuries for their immunomodulatory properties and therapeutic potentials. The present study aims to investigate the immunomodulatory constituents from traditional medicinal plant, Tinospora cordifolia (willd.).

Mortality Audit of Cancer Patients in the Department of Medical Oncology at a Tertiary Cancer Care Centre in South India.

Considerable advances in the diagnosis and treatment of cancer have made a huge impact on morbidity and mortality from neoplastic diseases. However, cancer remains the leading cause of death across the world. This is a retrospective study carried out at a tertiary cancer care centre (Kidwai Memorial Institute of Oncology, Bangalore) in South India.

Frequency of Programmed Death Receptor Ligand 1 Expression and Clinicopathological Factors Associated With Metastatic Triple-Negative Breast Cancer at a Tertiary Cancer Care Centre in South India.

Purpose Triple-negative breast cancer (TNBC) has a poor outcome compared to other subtypes. Immune checkpoint inhibitors (ICIs) have changed the treatment paradigm in metastatic diseases as well as in neoadjuvant setting. The response to these agents is affected by programmed death ligand 1 (PDL1) receptor expression which are reported objectively as a score.

Survey of the present health & nutritional status of Shompen tribe of Great Nicobar Island.

Background Objectives: Shompens are one of the two mongoloid tribes of Nicobar district. There is little information about their recent health status since the last survey which was conducted in 1998. Hence, a comprehensive health and nutritional survey was conducted in March 2017 to assess the changes.

Adenomyoepithelial adenosis mimicking phylloides: A diagnostic dilemma.

Benign proliferative breast diseases are well recognized in young females. Benign biphasic proliferation of epithelial and myoepithelial cells has been observed, among which adeno-myoepithelial adenosis is one of the rare morphologies published in the literature with the tendency to recur and poses a risk for low-grade malignant transformation. Here, we report a case of a young female who had a history of recurrent breast lump mimicking phyllodes tumor and eventually diagnosed as adeno-myoepithelial adenosis on histopathological examination.

Nanotechnological synergy of mangiferin and curcumin in modulating PI3K/Akt/mTOR pathway: a novel front in ovarian cancer precision therapeutics.

Ovarian cancer, colloquially termed the "silent killer" among gynecological malignancies, remains elusive due to its often-asymptomatic progression and diagnostic challenges. Central to its pathogenesis is the overactive PI3K/Akt/mTOR signaling pathway, responsible for various cellular functions, from proliferation to survival. Within this context, the phytochemical compounds mangiferin (derived from ) and curcumin (from ) stand out for their potential modulatory effects.

Canine retraction and anchorage loss using self-ligating and conventional brackets with sliding mechanics: A split-mouth clinical study.

Objective: Appliance biocompatibility, orthodontic treatment efficiency and patient convenience are the major issues confronting contemporary orthodontic practice. Very few studies have been published till date regarding the efficiency of self-ligating brackets as against conventional brackets. Hence, the present study was planned to compare the rate of canine retraction between self-ligating and conventional brackets and to determine the amount of anchorage loss during canine retraction.

Comparison of shear bond strength of composite resin, compomer, and resin-modified glass-ionomer cements in primary teeth: An study.

Objective: The contemporary esthetic restorative materials such as composite resin and glass-ionomer cements and their modifications have all been developed keeping in mind the requirements of permanent teeth. There have been plenty of studies that have focused on the characteristics of these materials in relation to permanent teeth with a relative dearth of such studies as regard to the primary teeth. The present study was undertaken to compare and evaluate the shear bond strength of composite resin, compomer, and resin-modified glass-ionomer cements in primary teeth.

Comparative evaluation of impact strength of mechanically modified heat polymerized polymethyl methacrylate (PMMA) resin with addition of 0.5, 1, 2 wt% of silver nanoparticles (AgNPs): An in-vitro study.

Objective: Polymethyl methacrylate (PMMA) is one of the most widely used denture base material because of favorable esthetics and desirable characteristics such as easy handling. Acrylic resins, although, have some inherent disadvantages such as relatively poor physical and mechanical properties. The objective of the present study was to evaluate and compare the impact strength of unmodified and modified heat cure PMMA-based denture base material with addition of different concentrations of silver nanoparticles (AgNPs) (0.

Comparative evaluation of variations in torque expression in maxillary incisor and canine using different bracket prescriptions placed at different crown levels by finite element (FE) method: An analysis.

Objective: While using preadjusted brackets, the position of the bracket on the crown is one of the deciding factors that determine the tooth's final tip, torque, height, and rotation. The final tooth position is not optimal if the bracket is placed incorrectly or if the varying crown morphology does not correspond with the bracket design. The present study was conducted to evaluate and compare the variations in torque expression in maxillary incisor and canine using different bracket prescriptions placed at different crown levels by finite element method.

Combined Use of Copernic RC Venous Remodeling Balloon and Aspiration Thrombectomy for Cerebral Venous Sinus Thrombosis.

Cerebral venous sinus thrombosis is a potentially fatal condition. The current first line of treatment for sinus thrombosis is anticoagulation. Endovascular treatment is an alternative for patients whose symptoms progress despite adequate medical management.

Understanding the Impact of Population and Cancer Type on Tumor Mutation Burden Scores: A Comprehensive Whole-Exome Study in Cancer Patients From India.

Purpose: The purpose of this study was to understand the impact of population diversity and geographic variation on tumor mutation burden (TMB) scores across cancers and its implication on stratification of patients for immune checkpoint inhibitor (ICI) therapy.

Materials And Methods: This retrospective study used whole-exome sequencing (WES) to profile 1,233 Indian patients with cancer across 30 different cancer types and to estimate their TMB scores. A WES-based pipeline was adopted, along with an indigenously developed strategy for arriving at true somatic mutations.

Expression of immune checkpoint protein in oral squamous cell carcinoma and its clinicopathological correlation: A tertiary care center cross-sectional study.

Background: Recent evidence suggests that oral squamous cell carcinoma (OSCC) patients who exhibit the immunohistochemical expression of immune checkpoint protein programmed cell death ligand 1 (PD-L1) are more likely to have a poor clinical outcome and may serve as an independent prognostic marker.

Aims And Objectives: This study aimed to assess the immunohistochemical expression of immune checkpoint protein PD-L1 in OSCC and its clinicopathological correlation.

Materials And Methods: OSCC cases were included in the study.

Assessment of submicron aerosol liquid water content and mass-based growth factors in South Asian outflow over the Indian Ocean.

Aerosol-bound water, a ubiquitous and abundant component of atmospheric aerosols, has an impact on regional climate, visibility, human health, the hydrological cycle, and atmospheric chemistry. Yet, the intricate relationship between aerosol liquid water (ALWC) and chemical composition and relative humidity (RH) was not well understood. The present study explores ALWC derived from the ISORROPIA II model using real-time, high-resolution data of non-refractory submicron chemical species and meteorological parameters (temperature and RH) collected over the Indian Ocean as part of the ICARB (Integrated Campaign for Aerosols, Gases, and Radiation Budget)-2018 experiment.