Hybridization of synergistic swarm and differential evolution with graph convolutional network for distributed denial of service detection and mitigation in IoT environment.

Enhanced technologies of the future are gradually improving the digital landscape. Internet of Things (IoT) technology is an advanced technique that is quickly increasing owing to the development of a network of organized online devices. In today's digital era, the IoT is considered one of the most robust technologies.

Sub-100 fs Formation of Dark Excitons in Monolayer WS.

Two-dimensional semiconducting transition metal dichalcogenides are promising materials for optoelectronic applications due to their strongly bound excitons. While bright excitons have been thoroughly scrutinized, dark excitons have been much less investigated, as they are not directly observable with far-field spectroscopy. However, with their nonzero momenta, dark excitons are significant for applications requiring long-range transport or coupling to external fields.

Validation of Low Cost Patient Specific Implant Design Using Finite Element Analysis (FEA) for Reconstruction of Segmental Mandibular Defects: A Case Report and Literature Review.

Introduction: Mandibular continuity defects can cause functional and cosmetic deformities affecting a patient's quality of life. Reconstruction of such defects can be intricate even for the most seasoned maxillofacial surgeons. Reconstruction plates were the standard of care in the past, followed by a secondary reconstruction using autogenous grafts.

Evolution, identification, evaluation, and characterization of a stable salinity tolerant sugarcane variety CoG 7.

From the fluff generated during 2005, after the preliminary experiments (2005-2007), a promising clone G2005047 has been identified. It showed moderate resistance to red rot (3.6 on a 9-scale scoring system), less susceptibility to shoot borer (13.

Artificial intelligence in medical education - perception among medical students.

Background: As Artificial Intelligence (AI) becomes pervasive in healthcare, including applications like robotic surgery and image analysis, the World Medical Association emphasises integrating AI education into medical curricula. This study evaluates medical students' perceptions of 'AI in medicine', their preferences for AI training in education, and their grasp of AI's ethical implications in healthcare.

Materials & Methods: A cross-sectional study was conducted among 325 medical students in Kerala using a pre-validated, semi structured questionnaire.

A comprehensive evaluation of water, sanitation and hygiene (WASH) in health facilities: a systematic review and meta-analysis.

Despite global recognition, WHO reports reveal significant gaps, with one in four healthcare facilities lacking basic water services, affecting over 1.8 billion people, and 21% lacking sanitation services, impacting 1.5 billion people, especially prevalent in low- and middle-income countries.

Solution Ionic Strength Can Modulate Functional Loop Conformations in Dihydrofolate Reductase.

The observation of multiple conformations of a functional loop (termed M20) in the dihydrofolate reductase (DHFR) enzyme triggered the proposition that large-scale motions of protein structural elements contribute to enzyme catalysis. The transition of the M20 loop from a conformation to an conformation was thought to aid the rate-limiting release of the products. However, the influence of charged species in the solution environment on the observed M20 loop conformations, independent of charged ligands bound to the enzyme, had not been considered.

Microbial community diversity of an integrated constructed wetland used for treatment of sewage.

The microbial community diversity in Constructed Wetland System (CWS) plays a key role in the removal of pollutants from waste water. An integrated functional CWS developed at Neela Hauz Biodiversity Park, Delhi was selected to assess the diversity in composition and structure of microbial community diversity of sludge and sediment of CWS, based on metagenomic approach using 16S rRNA genes. The sediment showed higher diversity than sludge and both formed distinct clusters.

Comparison of Janani Suraksha Yojana (JSY) and augmented Arogya Laxmi scheme (ALS) in improving maternal and child health outcomes in urban settlements of Hyderabad, South India.

Background: India accounts for the largest number of global neonatal deaths with around 20 per 1000 live births. To improve the utilization of government services for institutional deliveries, Augmented Arogya Laxmi Scheme (ALS) was launched in Telangana state of southern India. This study assessed the effectiveness of the Janani Suraksha Yojana (JSY), which combines cash assistance with delivery and post-delivery care, in comparison to ALS in improving the outcomes related to antenatal, natal, and postnatal care in urban settlements of Hyderabad, Telangana, southern India.

Higher Rates of Inadequate Adjuvant Radiation Dose Among Older Adults with Head and Neck Cancer.

Objective: To determine the rate of inadequate radiotherapy and identify risk factors associated with inadequate adjuvant radiotherapy for head and neck cancer among older adults.

Methods: A retrospective review of the National Cancer Database (NCDB) was performed to identify patients diagnosed with squamous cell cancer of the head and neck between 2004 and 2017. Patients with a single malignancy, negative surgical margins, no extranodal extension, and receipt of adjuvant radiation without systemic therapy were included in the study cohort.

Groundwater and pore water inputs to the Bay of Bengal supported by geochemical tracers: Example from Tamil Nadu and Pondicherry, East Coast of India.

Submarine groundwater discharge (SGD) and Saline water intrusion (SWI) are the two major processes that influence coastal aquifers resulting in severe water stress. It is essential to characterize groundwater dynamics and discriminate geochemical characterization to understand both approaches. The present study investigates the zones influenced by SGD and SWI along the coastal aquifers of Tamil Nadu and Pondicherry.

Arbuscular mycorrhizas accelerate the degradation of colour containing organic pollutants present in distillery spent wash leachates.

Distillery spent wash (DSW) from molasses-based distilleries is being used as a low-cost alternative to chemical fertilizers in countries like India and Brazil. However, using DSW as a fertilizer substitute causes organic pollutant leaching, including melanoidins and caramel colourants that turn bodies of water dark brown. This study investigated the arbuscular mycorrhiza (AM) mediated degradation of organic pollutants in DSW.

Additive risk of surgical site infection from more than one risk factor following craniotomy for tumor.

Purpose: This study seeks to expound upon risk factor etiologies for surgical site infection (SSI) and investigate their combinatorial effects on infection rate following craniotomy for neuro-oncologic pathology.

Methods: Patients who underwent neuro-oncologic craniotomy between 2006 and 2020 were included. Medical records were reviewed to identify the occurrence of wound infection at ≤ 3 months postoperatively.

Assessment of Exercise Capacity of Individuals with Long COVID: A Cross-sectional Study.

Background: Clinical investigations of long-term effects of coronavirus disease 2019 (COVID-19) are rarely translated to objective findings.

Objectives: To assess the functional capacity of individuals reported on deconditioning that hampered their return to their pre-COVID routine.

Methods: Assessment included the 6-minute walk test (6MWT) and the 30-second sit-to-stand test (30-STST).

A review of biological targets and therapeutic approaches in the management of triple-negative breast cancer.

Background: Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive phenotype of breast cancer with associated chemoresistance. The development of chemo- or radioresistance could be attributed to diverse tumor microenvironments, overexpression of membrane proteins (transporters), epigenetic changes, and alteration of the cell signaling pathways/genes associated with the development of cancer stem cells (CSCs).

Aim Of Review: Due to the diverse and heterogeneous nature of TNBC, therapeutic response to the existing modalities offers limited scope and thus results in reccurance after therapy.

Meloxicam in Combating Clinical Mastitis: Nanotechnology-Driven Hope and Opportunities.

Mastitis has well-recognized harmful effects on dairy farm profitability. Furthermore, mastitis impairs the milk component synthesizing ability of secretary tissues. Various therapies are available for the treatment of clinical mastitis.

Computational and experimental therapeutic efficacy analysis of andrographolide phospholipid complex self-assembled nanoparticles against Neuro2a cells.

Background: Neuroblastoma is one of the most common malignancies in childhood, accounts for approximately 7% of all malignancies. Andrographolide (AN) inhibits cancer cells progression via multiple pathways like cell cycle arrest, mitochondrial apoptosis, NF-κβ inhibition, and antiangiogenesis mechanism. Despite multiple advantages, application of AN is very limited due to its low aqueous solubility (6.

Maternal Nutrition, Body Composition and Gestational Weight Gain on Low Birth Weight and Small for Gestational Age-A Cohort Study in an Indian Urban Slum.

Maternal nutritional status and care during pregnancy are essential for adequate birth weight. In this prospective cohort study (N = 1061) in an urban slum, we investigated the association of maternal anthropometry, body composition, gestational weight gain and dietary intakes with low birthweight (LBW, <2.5 kg).

Semantic relational machine learning model for sentiment analysis using cascade feature selection and heterogeneous classifier ensemble.

The exponential rise in social media microblogging sites like Twitter has sparked curiosity in sentiment analysis that exploits user feedback towards a targeted product or service. Considering its significance in business intelligence and decision-making, numerous efforts have been made in this area. However, lack of dictionaries, unannotated data, large-scale unstructured data, and low accuracies have plagued these approaches.

Fumigant and contact toxicities of individual and additive combinations of biorational-essential oils for control of rice weevil (.

Fumigant and contact activity of individual and combination of EOs (cumin seed and black pepper oil) were conducted against rice weevil (). Cumin seed and black pepper oil individually exhibited 100% insecticidal activity (Contact and Fumigant) against at 24 and 168 h of exposure in the absence and presence of food, respectively. Overall, differential insect mortality rates were observed with individual EOs; however, cumin seed EO showed higher insecticidal activity in both fumigant and contact bioassays than black pepper EO.