Changes in knot-holding capacity of sliding knots in vivo and tissue reaction.

Objectives: To evaluate and compare the in vivo strength, knot efficiency, and knot security of 4 types of sliding knots, and to assess tissue reaction to study the effect of knot configuration, knot volume, and suture size.

Design: Randomized trial.

Setting: Experimental Medical Research Institute, Istanbul, Turkey.

Knot properties of alternating sliding knots with different patterns in comparison to alternating and simple sliding knots.

This study attempts to compare the alternating sliding knots with different patterns with the alternating and simple sliding knots. Silk and nylon sutures of 2-0 and 4-0 United States Pharmacopeia (USP) sizes were mechanically tested. The values of knot holding capacities (KHCs) varied depending on knot configuration, suture material, and size.