Objectives: Aqueous leaf extract of (ALETP) has potent relaxant activity. However, this relaxant activity in respiratory smooth muscle remains uninvestigated. This study investigates the effect of ALETP on the contractile activity of tracheal smooth muscle (TSM) in adult male Wistar rats.
View Article and Find Full Text PDFIntroduction: Carpolobia lutea root extract (CLRE) has been reported to enhance penile erection. However, the mechanism involved is poorly understood. We investigated in vitro mechanisms of CLRE action on contractile activity of rabbit corpus cavernosum (CC).
View Article and Find Full Text PDFEvid Based Complement Alternat Med
August 2019
Background: In this study, the male fertility-enhancing activity of 100, 200, and 400 mg/kg/day of water seed extract () in Wistar rats was studied for 60 days. In doing this, effect of repeated doses of was studied on the weight gain pattern, gonadosomatic index (GSI), serum follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (TS), prolactin (PRL), and estradiol (ES)} as well as testicular antioxidant status of the treated rats as a way of elucidating the mechanism(s) of action of .
Method: Thirty-six (36) male Wistar rats were randomly divided into six groups (I-VI) of six rats per group.
J Integr Med
January 2018
Objective: This study investigated the effects of aqueous leaf extract of Tridax procumbens (ALETP) on contractile activity of corpus cavernosum in N-nitro-l-arginine methyl ester (l-NAME)-induced hypertensive male rats.
Methods: Twenty normal, adult male rats (130-150 g) were divided into four groups of five rats each. Group I (control) was given normal saline (0.